手术联合放射治疗小涎腺恶性肿瘤的疗效观察  

Clinical Efficacy of Operation Combined with Radiotherapy for Minor Salivary Gland Malignant Carcinoma

作　　者：柳锋[1] 胡礼明[1] 黄卫东[1] 胡丽曼[1] 张华萍[1] 

机构地区：[1]湖北省孝感市中心医院,432000

出　　处：《实用癌症杂志》2014年第5期596-598,共3页The Practical Journal of Cancer

摘　　要：目的：探讨手术联合放射治疗小涎腺恶性肿瘤的疗效。方法回顾性分析64例小涎腺恶性肿瘤患者的临床资料，随机分为手术加放疗组（n＝32）和单纯手术治疗组（n＝32），比较2组患者术后复发、远处转移率以及近10年内的生存率差异。结果手术加放疗组术后复发率（12．50％）及远处转移率（15．63％）均显著低于单纯手术治疗组（P＜0．05）；术后2～10年的生存率均显著高于单纯手术治疗组（P＜0．05）。放疗剂量50～60 Gy组10年生存率（73．33％）明显高于其他剂量组（P＜0．05）。结论手术联合放射治疗小涎腺恶性肿瘤可显著提高患者术后生存率，其中术后辅助放疗剂量以50～60 Gy效果最佳。Objective To explore the efficacy of operation combined with radiotherapy for minor salivary gland malignant carcinoma.Methods Clinical data of 64 cases of minor salivary gland malignant carcinoma were retrospectively analyzed .64 pa-tients were randomly divided into operation plus radiotherapy group （ n=32 cases） and simple operation group （ n=32）;postop-erative recurrence ,distant metastasis rates and nearly 10-year survival rates of the 2 groups were compared .Results The recur-rence rate（12.50%）and distant metastasis rate（15.63%）of the operation plus radiotherapy group were significantly lower than those of the simple operation group （P〈0.05）;postoperative 2~10 years survival rates of the operation plus radiotherapy group were significantly higher than those of the simple operation group （ P〈0.05）;and the radiation dose 50~60 Gy group,10-year survival rate（73.33%） was significantly higher than other groups （P〈0.05）.Conclusion Operation combined with radiother-apy for minor salivary gland malignant carcinoma can obviously enhance survival rates of patients ,and postoperative radiotherapy dose is the best at 50~60 Gy.

关 键 词：小涎腺恶性肿瘤 手术 放疗 剂量 生存率 

分 类 号：R739.87[医药卫生—肿瘤]