非乙醇性脂肪肝病患者身体成分及其危险因素分析  

The body composition and risk factors analysis in non-alcoholic fatty liver patients

作　　者：蒋建华[1] 张宝[1] 管石侠[1] 侯丽丽[1] 唐芸[1] 

机构地区：[1]安徽医科大学第一附属医院临床营养科,合肥230022

出　　处：《中国临床保健杂志》2014年第6期574-576,共3页Chinese Journal of Clinical Healthcare

基　　金：安徽省科技年度项目(1301043019)

摘　　要：目的：探讨非乙醇性脂肪肝病（NAFLD）患者与正常人群身体成分的差异及 NAFLD 的危险因素。方法选择40～69岁 NAFLD 患者172例，179名体检健康者（对照组）；分别测量两组的身体成分和血生化指标。结果NAFLD 组细胞内液百分比、细胞外液百分比（ECW％）、蛋白质百分比、无机盐百分比、细胞外液与细胞内液比及高密度脂蛋白胆固醇均低于对照组（P ＜0．05），而体脂肪百分比、体质量指数、腰围、臀围、腰臀比（WHR）及内脏脂肪面积、空腹血糖、总胆固醇、三酰甘油（TG）、极低密度脂蛋白胆固醇、低密度脂蛋白胆固醇均高于对照组，差异有统计学意义（P ＜0．05）。Logistic 回归分析显示，WHR、ECW％、TG 与NAFLD 具有相关性。结论NAFLD 患者的人体成分与健康人相比存在差异，代谢紊乱明显；NAFLD 的发生可能与腹型肥胖、细胞外液百分比减少及高三酰甘油血症存在一定的关系。Objective To explore the risk factors for NAFLD between the non-alcoholic fatty liver disease （NAFLD）patients and normal population.Method One hundred and seventy two cases with NAFLD and 1 79 healthy cases （control group）aged between 40 to 69 were collected;The body composition and serum biochemical were measured in both groups.Results The percentage of intracellular fluid （ICW%）,percentage of extracellular fluid （ECW%）,protein percentage （Protein%）,inorganic salts percentage （Mineral%）,extracellular fluid and in-tracellular fluid ratio （ECW/ICW）,high-density lipoprotein cholesterol （HDL-C）of NAFLD were lower than those of the control group （P 〈0.05）（body fat%）,and the body fat percentage,body mass index （BMI）,waist circumfer-ence （WC）and hip circumference （HC）,waist hip ratio （WHR）and visceral fat area （VFA）,fasting plasma glu-cose （FPG）,total cholesterol （TC）,triglyceride （TG）,very low density lipoprotein cholesterol （VLDL-C）,low-den-sity lipoprotein cholesterol （LDL-C）were those of higher than the control group （P 〈0.05）.The logistic regression analysis showed that WHR,TG ECW% were related with NAFLD.Conclusions The body composition of NAFLD is different with healthy people.The NAFLD may be related to abdominal type obesity,extracellular fluid percentage re-duction and hypertriglyceridemia.

关 键 词：脂肪肝 身体成分 危险因素 

分 类 号：R575.5[医药卫生—消化系统]