膀胱肿瘤患者术后医院感染情况的调查与分析  

Investigation and analysis on nosocomial infection following bladder tumor operation

作　　者：谢红艳[1] 凃敏[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院医院感染管理科,武汉430030

出　　处：《现代泌尿生殖肿瘤杂志》2014年第5期287-289,共3页Journal of Contemporary Urologic and Reproductive Oncology

摘　　要：目的了解膀胱肿瘤患者术后医院感染的发生率、危险因素、病原菌及其耐药率,为预防术后感染提供科学依据。方法用回顾性调查方法,收集2010年1月至2013年12月我院泌尿外科施行膀胱肿瘤手术（包括膀胱肿瘤电切术、膀胱部分切除术和膀胱根治性切除术）患者的临床资料、微生物检查结果,并对相关资料进行统计分析。结果膀胱肿瘤术后医院感染发生率为8.8%,其中泌尿系感染以革兰阴性菌为主（71.1%）,其对三代头孢菌素和喹诺酮类耐药率达40%-50%;术后医院感染与患者年龄、住院时间、术前尿路感染、手术时间、导尿管留置时间、有无糖尿病及是否恶性肿瘤密切相关（Ρ〈0.05）。结论应整合一系列有严格循证医学证据和基础的防控方案,制定出合理的干预策略,并进行早期干预,以期达到有效降低术后感染的目的。Objective To investigate the risk factors,pathogenic bacteria and their drug resistance of nosocomial infection following bladder tumor resection. Methods The clinical data and microbial inspection results in patients who underwent bladder tumor resection were investigated by retrospective survey from Jan 2010 to Dem 2013. Results The incidence rate of nosocomial infection following bladder tumor was 8.8%.The majority of pathogens in urinary tract infection were gram-negative bacteria（71.1%）.The rate of drug-resistance among these pathogens to three generation cephalosporin and quinolones reached 40%-50%.There were positive correlation between nosocomial infection following bladder tumor with the age,length of hospital stay,preoperative urinary tract infection,operation time,duration of postoperative catheter retention,diabetes and malignant tumor（Ρ〈0.05）. Conclusions We should integrate a series of preventive schedule with strict evidence and foundation based medicine and formulate cluster intervention strategies,and should carry out the early intervention,so as to achieve the purpose of effectively reduce postoperative infection.

关 键 词：膀胱肿瘤 手术 医院感染 危险因素 

分 类 号：R737.14[医药卫生—肿瘤]