抗血小板药物相关上消化道出血临床特点研究  

作　　者：王溶[1] 

机构地区：[1]四川省宜宾市第三人民医院消化内科,四川宜宾644000

出　　处：《临床医药文献电子杂志》2014年第9期723-723,725,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的研究抗血小板药物相关上消化道出血的临床特征。方法选取2011年5月至2012年6月我院收治的120例非静脉曲张上消化道出血患者作为研究对象,对以上120例患者的临床资料进行回顾性分析,根据患者在治疗过程中是否使用抗血小板药物进行分组,分为实验组与对照组,实验组患者在治疗过程中使用抗血小板药物,观察组在治疗过程中并未使用抗血小板药物,并对两组患者的临床资料进行比较,结果 120例非静脉曲张上消化道出血患者中37例患者服用过抗血小板药物。患者的性别、饮酒史、HP感染情况等一般资料比较,无显著性差异(P>0.05),而实验组中多数患有高血压,冠心病等心脑血管疾病,患者临床表现不一(P<0.05)。结论患者的年龄,高血压等心脑血管病史是抗血小板药物相关上消化道出血的高危因素。Objective Clinical characteristics of gastrointestinal hemorrhage of upper digestive antiplatelet drug related. Methods The gastrointestinal bleeding patients as the research object and 120 cases of non varicose vein from 2011 May to 2012 June in our hospital were on the digestion, the clinical data of 120 patients were analyzed retrospectively, according to whether the process in the treatment of patients with antiplatelet agents are grouped, divided into the experimental group and the control group, the experimental group patients antiplatelet drugs in the course of treatment, the observation group in the treatment process did not use of antiplatelet drugs, and the clinical data of the two groups were compared. Results Taking antiplatelet drugs in 37 patients with gastrointestinal bleeding and 120 cases of non variceal upper gastrointestinal. Patient sex, history of drinking, the situation of Hp infection in general data showed no significant difference （P＆gt; 0.05）, while the experimental group in the majority of patients with hypertension, coronary heart disease and other cardiovascular and cerebrovascular diseases, the clinical manifestations of the patients is not a （P〉0,05）. Conclusion The patients age, hypertension and other cardiovascular and cerebrovascular disease are risk factors of hemorrhage of upper digestive tract antiplatelet drugs.

关 键 词：抗血小板药物 上消化道出血 临床特点 

分 类 号：R573.2[医药卫生—消化系统]