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机构地区:[1]东营市第二人民医院妇产科,山东东营257335 [2]济南军区总医院妇科,山东济南250031
出 处:《中华肿瘤防治杂志》2014年第22期1774-1777,共4页Chinese Journal of Cancer Prevention and Treatment
基 金:2010年山东省东营市政府资助项目(DY0107)
摘 要:目的探讨山东省东营地区农村中老年妇女宫颈癌发病特点和防治对策。方法对东营地区2010-03-01-2013-10-31已婚或有性生活史的农村35-60岁18 365名妇女进行宫颈病变筛查资料分析,检查项目包括妇科检查、彩色超声、阴道及宫颈分泌物涂片显微镜检查和宫颈脱落细胞液基薄层细胞学(thinprep cytologic test,TCT)检测,对检查可疑或异常者,再进行阴道镜和宫颈组织病理学检查。结果查及各种妇科疾病占26.11%(4 796/18 365),其中生殖道炎症占16.23%(2 980/18 365),宫颈上皮内瘤样病变(cervical intraepithelial neoplasia,CIN)占3.79%(697/18 365),宫颈癌占0.15%(28/18 365)。各级CIN和浸润癌发病中位数年龄均位于41-50岁年龄组,浸润癌检出率在35-40和41-50岁组,与51-60岁组差异无统计学意义(P〉0.05),具有显著的年轻化趋势。CINⅠ中位数年龄为42.5岁,CINⅡ为45.5岁,CINⅢ为48.5岁,宫颈浸润癌为49.5岁。结论东营地区CIN和宫颈癌检出率较高。应该加大免费筛查力度,有针对性地对不同年龄段开展宫颈癌检查,提高CIN和宫颈癌诊断的效率,并对筛查出的宫颈癌和CIN积极治疗随访,有效阻断宫颈癌的发生。OBJECTIVE To investigate the epidemiological condition of cervical carcinoma in elderly women in rural areas of Dongying City in Shandong Province. METHODS A total of 18 365 women were collected and analyzed by gyne- cological examination, color ultrasound, vaginal and cervical secretions smear microscopy examination, cervical exfoliated cells of liquid based cytology (TCT) detection. The women with suspicious or abnormal results were examined by colpos- copy and cervical tissue multipoint biopsy. RESULTS Totally 4 796 cases out of 18 365 women were detected with gynaecologic diseases(26.11%), including genital tract inflammation 16.23%(2 980/18 365), cervical intraepithelial neo- plasia(CIN) 3.79% (680/18 365), cervical cancer 0.15%(28/18 365). The median ages of CIN and invasive cancer were both located in the 41 to 50 age group. The incidence of invasive cancer in 35-40 and 41-50 years-old group were not significantly higher than that of 51-60 years-old group(P〉0.05). The median age of CIN Ⅰ , Ⅱ , Ⅲ and invasive cervi- cal carcinoma were respectively in 42.5, 45.5, 48.5 and 49.5 years-old groups. CONCLUSIONS CIN and cervical cancer incidence of Dongying is still high. Intensify efforts to free screening, targeted to develop cervical cancer check for differ- ent age groups can improve the efficiency of CIN and cervical cancer diagnosis. Correct treatment and follow-up of screened cervical cancer and CIN can effectively decrease the occurrence of cervical cancer.
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