Rathke囊肿并垂体腺瘤2例报告并文献复习  

Rathke cyst complicated by pituitary adenoma: a two-case report and literature review

作　　者：王雷[1] 王峻[1] 简志宏[1] 易伟[1] 连海伟[1] 余信远[1] 刘仁忠[1] 

机构地区：[1]武汉大学人民医院神经外科,武汉430060

出　　处：《中国微侵袭神经外科杂志》2014年第12期546-548,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的总结垂体腺瘤伴Rathke囊肿的临床特征与治疗方法。方法回顾性分析2例经手术病理证实伴有Rathke囊肿的垂体腺瘤病例资料。结合临床特征、影像学表现、手术治疗以及相关文献进行分析。结果 2例病人均经翼点入路行开颅手术,术后病理结果为垂体腺瘤合并Rathke囊肿。1例术后随访13个月复查MRI示未见肿瘤及囊肿复发,1例术后视力较术前好转。结论伴有Rathke囊肿的垂体腺瘤临床罕见,鞍区MRI提示垂体腺瘤旁存在囊性信号应考虑合并Rathke囊肿。临床明确诊断依赖于组织病理学观察及免疫组化标记。对于压迫症状明显且伴有Rathke囊肿的垂体腺瘤可手术治疗。Objective To summarize clinical features and treatment methods for pituitary adenoma combined with Rathke cyst. Methods The clinical data of 2 patients with pathologically confirmed pituitary adenoma combined with Rathke cyst were analyzed retrospectively. The clinical features, imaging findings and surgical treatment were analyzed and related literatures reviewed. Results The tumor was removed in a pterional craniotomy in the two patients. The postoperative pathological examination showed pituitary adenoma with Rathke cyst. The postoperative follow-up time of 13 months and MRI showed no tumor or cyst recurrence in one patients and visual acuity of one case was improved following surgical operation in the other one. Conclusions Pituitary adenoma associated with Rathke cyst is clinically rare. Rathke cyst should be taken into account if pituitary MRI suggests cystic signal. The diagnosis relies on immunohistochemical markers and histopathological observation. Surgical treatment can be taken for obvious compression symptoms in pituitary adenoma combined with Rathke cyst.

关 键 词：垂体肿瘤 中枢神经系统囊肿 神经外科手术 

分 类 号：R739.41[医药卫生—肿瘤]