输精管结扎与前列腺癌发病相关性Meta分析  

Relationship between vasectomy and prostate cancer:a meta-analysis

作　　者：颜克钧[1] 李有元[1] 刘昌荣[1] 向天一[1] 喻俊锋[1] 李爱军[1] 孙德明[1] 蒋林涛[1] 易成[1] 

机构地区：[1]三峡大学人民医院泌尿外科,湖北宜昌443000

出　　处：《临床泌尿外科杂志》2014年第12期1061-1063,1066,共4页Journal of Clinical Urology

基　　金：宜昌市科技发展计划项目(编号A06412)

摘　　要：目的：探讨输精管结扎与前列腺癌发病间的相关性。方法：以＂输精管结扎术＂、＂前列腺癌＂及其同义词和近义词为关键词,在CBMDisc、CMCC、CMAC、CNKI（1978年~2014年1月1日）和PubMed（1965年~2014年1月1日）等国内外数据库上进行全面检索,按文献纳入及剔除标准筛选出符合要求的文献,采用Meta分析方法进行综合分析。结果：共有17篇病例对照研究文献纳入本次研究,符合研究标准的研究对象33 841例,其中病例12 243例,对照21 598例。合并OR值（95%CI）为1.03（0.87,1.23）。结论：输精管结扎不增加前列腺癌的发病风险。Objective：To investigate the correlation between vasectomy and occurrence of prostate cancer.Method：The databases of CBMDisc,CMCC,CMAC,CNKI（from 1978 to January 1st,2014）and PubMed（from1965to January 1st,2014）were searched using the key words ＂vasectomy＂ and ＂prostate cancer＂.The literature was selected according to the literature inclusion and exclusion criteria.Then the selected literature adopted a comprehensive analysis of the meta-analysis methods.Result：A total of 17case-control studies were included in this investigation.There were total 33 841 cases met the study criteria.Among the total cases,there were 12 243 cases with prostate cancer and 21 598 cases as controls.The overall pooled OR（95%CI）was 1.03（0.87,1.23）.Conclusion：Vasectomy does not increase the risk of prostate cancer.

关 键 词：前列腺癌 输精管结扎术 相关性 META分析 

分 类 号：R737.25[医药卫生—肿瘤]