不同人工晶状体行后囊后嵌顿术的实验研究  

Experimental study on different intraocular lens in posterior capsular optic capture

作　　者：尤昌俊 温跃春 

机构地区：[1]安徽医科大学附属省立医院眼科,安徽省合肥市230001

出　　处：《眼科新进展》2014年第12期1120-1123,共4页Recent Advances in Ophthalmology

基　　金：卫生部"视觉第一中国行动"项目三期(编号:sfca-13-2013-01)~~

摘　　要：目的对比3种不同人工晶状体植入术后对幼兔眼前节炎症反应、人工晶状体位置及后囊膜混浊的影响,为儿童后囊后人工晶状体嵌顿术选择合适的人工晶状体。方法 1月龄新西兰白兔36只,随机分成A、B、C 3组,均行右眼晶状体吸出+后囊膜连续环形撕囊联合人工晶状体后囊后嵌顿术,其中A组植入硬片式人工晶状体;B组植入三片式软性人工晶状体;C组植入单片式软性人工晶状体。术后1 d、1周、1个月、3个月分别行术眼的裂隙灯、UBM及眼前节照相检查。结果术后1周时A组的眼前节炎症反应较B组、C组重,差异均有统计学意义(P=0.03、0.03)。术后3个月时A组有2眼人工晶状体夹持,10眼正位;B组11眼正位,1眼偏位;C组2眼正位,8眼偏位,2眼夹持;人工晶状体正位率A组、B组之间差异无统计学意义(P>0.05),但与C组间差异均有统计学意义(P=0.03、0.01)。术后3个月时,A组、C组均有2眼出现后囊膜混浊,余术眼后囊膜均保持清亮,后囊膜混浊发生率3组间差异无统计学意义。结论襻为聚丙烯材料、光学部为丙烯酸酯(Acrylic)的三片式人工晶状体更适合儿童后囊后嵌顿术,对维持人工晶状体正位有积极作用。Objective To compare the effects of three different intraocular lens （IOL） on IOL position, anterior segment inflammation and posterior capsular opacifica- tion after surgery, and choose the appropriate IOL for the treated subjects underwent anterior and posterior capsulorrhexis combined with IOL implantation during the cataract surgery. Methods Thirty-six New Zealand rabbits were separated into three groups randomly. All rabbits were received posterior curvilinear capsulorhexis with optic capture of posterior chamber IOL, PMMA IOL was implanted in group A, three-pieces and Acrylic IOL in group B,sigie-piece Acrylic IOL in group C. All surgical animals were checked with slit lamp, UBM and anterior photocamera at 1 day, 1 week, 1 month, 3 months after the surgery. Results At postoperative 1 week, there were significant differences in the eye anterior segment inflammation between group A and group B, C （P =0.03,0.03 ）. At postoperative 3 months,IOL were clamped in 2 eyes of group A, and 2 eyes in group C; 10 eyes were in positive position in group A, 11 eyes in group B and 2 eyes in group C; 1 eye was found deflection in group B and 8 eyes in group C. There was no significant difference between group A and B （P 〉 0.05 ）, but there were significant differences between group A and C （ P = 0. 03,0. 01 ）. At postoperative 3 months,2 eyes developed posterior capsular opacification in group A and B, other eyes remained clear,there was no significant difference in posterior capsular opacification among three groups. Conclusion The three-piece Acrylic IOL is more suitable to posterior capsular optic capture, which has the positive effect on maintaining the positive position of IOL.

关 键 词：白内障 人工晶状体 环形撕囊 后囊膜混浊 

分 类 号：R776.1[医药卫生—眼科]