氯吡格雷联合阿司匹林治疗短暂性脑缺血发作的疗效  

Effect of Clopidogrel combined with aspirin on Transient Ischaemia Attack

作　　者：李晓泽[1] 

机构地区：[1]山西医科大学教学医院太原市中心医院神经内科,山西太原030009

出　　处：《吉林医学》2014年第34期7582-7583,共2页Jilin Medical Journal

摘　　要：目的:观察在抗血小板治疗基础上加用氯吡格雷治疗短暂性脑缺血发作(TIA)的疗效。方法:69例TIA患者随机分为治疗组、对照组,对照组在阿司匹林治疗的基础上,给予奥扎格雷钠治疗,疗程14 d;治疗组在以上治疗基础上给予氯吡格雷治疗,疗程7 d;疗程结束后加用阿司匹林100 mg,1次/d,口服,其余治疗相同。结果:治疗组总有效率明显高于对照组(P<0.05)。结论:在阿司匹林抗血小板治疗基础上,加用氯吡格雷治疗能改善TIA治疗效果,且安全性高,不良反应小。Objective To evaluate the effect of Clopidogrel on Transient Ischacmia Attack on the basis of antiplatelet therapy. Method Sixty - nine TIA patients were randomly divided into the treatment group and the control group. Patents in the two groups were treated with Aspirin 100 rag,once per day. Ozagrel were given to patients in the two groups for 14 days, Clopidogrel were given to patients for 7 days in the treatment group. Results The curative effect of TIA in the treatment group was significant higher than in the control group （P 〈 0.05 ） Conclusion Compared with the control group, Clopidogrel shows superiority in therapy of TIA.

关 键 词：脑缺血发作 短暂性 阿司匹林 奥扎格雷 氯吡格雷 

分 类 号：R743.31[医药卫生—神经病学与精神病学]