8～10岁矫正视力正常儿童黄斑区脉络膜厚度值及其影响因素  

Choroidal thickness and its relevant factors in 8-10 years old children with normal vision

作　　者：李环宇[1,2] 冯旺强[1] 查屹[1] 郑海华[1] 

机构地区：[1]温州医科大学附属第二医院眼科,325027 [2]湖南省常德市第一人民医院,415003

出　　处：《中华眼视光学与视觉科学杂志》2014年第11期666-670,共5页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：浙江省科技厅公益技术应用研究项目（2010C33013）;温州市科技局工业开发项目（G20100197）

摘　　要：目的 测量8～10岁矫正视力正常儿童黄斑区脉络膜厚度（CT）值,分析其影响因素.方法 横断面研究.选取75例（150眼）8～10岁矫正视力正常儿童志愿者,根据不同的屈光度分为远视组、正视组和近视组;采用三分位法根据眼轴长度分为20.35～22.42 mm组（D1组）,＞22.42～24.49 mm组（D2组）,＞24.49～26.56 mm组（D3组）;运用EDI SD-OCT对受检者后极部黄斑中心凹水平和垂直两个方向进行扫描;收集黄斑中心凹下（SF）距中心凹1 mm和3 mm处鼻侧（N）颞侧（T）上方（S）下方（Ⅰ）的CT值,分别记为SF、N1、T1、S1、I1,N3、T3、S3、I3.分析受检者不同方位及性别、眼别、屈光度组、眼轴组CT值变化情况,运用直线相关分析影响因素与CT值的相关性.结果 受检者SFCT值为（297.44±55.32）μm,各方位中仅N1、N3、I3与其比较有统计学意义（P＜0.05）;女性受检者SFCT值高于男性（t=-3.00,P＜0.01）.女性远视组与正视、近视2组相比差异有统计学意义（P＜0.05）,正视、近视2组间差异无统计学意义（P＞0.05）;而男性近视、正视、远视组间比较差异均无统计学意义（P＞0.05）;相关性分析发现：所有受检者屈光度与SFCT值呈正相关（r=0.435,P＜0.05）,眼轴与SFCT值呈负相关（r=-0.542,P＜0.05）;直线回归分析结果显示受检者SFCT值随眼轴增长而下降,眼轴每增加1 mm,SFCT值下降23.58 μm（Y=848.82-23.58X）.结论 8～10岁视力正常儿童SFCT值为（297.44±55.32）μm,眼轴是其主要影响因素.Objective To observe choroidal thickness （CT） and its relationship to refraction and axial length （AL） in children 8-10 years old with normal vision.Methods In this cross-sectional study,75（150 eyes） 8-10 years old children with normal vision were enrolled.Standard optometric refractive error was used to divide the children into three groups,a hyperopic group （A）,an emmetropic group （B） and a myopic group （C）.Using axial length （AL） tertiles,the children were divided into the following groups：20.35-22.42 mm group （D1）,＞22.42-24.49 mm group （D2）,and ＞24.49-26.56 mm group （D3）.Thickness in the enhanced images of the EDI SD-OCT apparatus can be obtained with a cross-sectional view of the choroid by using the scan line distance from the fovea with both horizontal and vertical scans.The choroidal thicknesses from the 9 macular sectors were used.Subfoveal choroidal thickness （SFCT） and CT at 1 mm/3 mm nasal,temporal,superior,and inferior to the fovea （N1,T1,S1,I1,N3,T3,S3,I3） were measured.The differences in CT between the different quadrants were compared for gender,eyes,refraction and AL.Results The average SFCT was 297.44±55.32 μm.When the SFCT was compared to each of the CT quadrants,only N1,N3 and I3 showed statistically significant differences （P＜0.05）.The differences in the SFCT values between girls and boys were statistically significant （t=-3.00,P＜0.01）.SFCT values for hyperopic girls were greater than for emmetropic and myopic girls.The differences were statistically significant （P＜0.05）.The difference between emmetropic and myopic girls was not statistically significant （P＞0.05）.There were no statistically significant differences between the refractive groups of boys （P＞0.05） or for their different axial length groups （P＞0.05）.There was a positive correlation between refractive status and SFCT （r=0.435,P＜0.05）.And there was a negative correlation between SFCT and AL （r=-0.542,P＜0.05）.Multiple linear regres

关 键 词：脉络膜厚度 黄斑 屈光不正 儿童 体层摄影术 光学相干 眼轴 

分 类 号：R770.4[医药卫生—眼科]