新藤黄酸抗肿瘤作用的研究进展  

Advances in anti- tumor effects of Neogambogic acid

作　　者：何烨 王科明[2] 

机构地区：[1]芜湖市第二人民医院,江苏芜湖241000 [2]南京医科大学第二附属医院,江苏南京210029

出　　处：《现代肿瘤医学》2015年第1期126-128,共3页Journal of Modern Oncology

基　　金：江苏省六大人才高峰项目(编号:WSN-050);南京市医学科技发展基金一般项目(编号:YKK13178)

摘　　要：藤黄酸(gambogic acid,GNA)的抗肿瘤作用已经有较为广泛而深入的研究,然而对藤黄的另一重要成分新藤黄酸(neogambogic acid,NGA)的抗肿瘤作用仍有待进一步探索。目前NGA的抗肿瘤作用已初步在学界达成共识,本文将着重讨新藤黄酸在各类肿瘤治疗研究中的最新进展,介绍其剂型和药物代谢动力学研究,并对其在治疗中的作用机制进行简单阐述。The anti-tumor effects of gambogic acid（ GNA）has a wide and deep research. However,the anti-tumor effects of neogambogic acid（ NGA,another important component of gamboge）still needs further exploration. The anti-tumor effects of NGA has reached a preliminary consensus in academia currently. This article focuses on the latest de-velopments of research to discuss NGA in the treatment of various types of cancers,introduce its formulation and phar-macokinetic studies and its mechanism of action in the treatment briefly.

关 键 词：新藤黄酸 抗肿瘤 进展 

分 类 号：R730.5[医药卫生—肿瘤]