柠檬提取物漱口液在儿童牙菌斑中的应用效果  

Effect of Lemon Peel Extract Mouth Rinses in Children's Dental Plaques

作　　者：姬长兰[1] 张向宇[2] 王玉芝[2] 余志芬[2] 汪大照[2] 

机构地区：[1]天津市儿童医院口腔科,300074 [2]天津医科大学口腔医院

出　　处：《中国全科医学》2014年第29期3511-3513,共3页Chinese General Practice

摘　　要：目的探讨柠檬提取物漱口液在儿童牙菌斑中的应用效果。方法选取2011年3月—2013年3月在天津市儿童医院口腔科门诊和病房就诊的龋齿病患儿120例,按照随机数字表法分为A、B、C 3组,每组40例。A组给予柠檬提取物漱口液漱口,B组给予复方醋酸氯己定漱口水漱口,C组给予康师傅纯净水漱口。记录3组患儿治疗前及治疗后1、2、3周时牙菌斑指数(PI)及治疗相关不良反应。结果 3组患儿治疗前及治疗后1、2、3周时PI比较,差异有统计学意义(F时间=21.670,F组间=3.430,F交互=7.329;P时间=0.001,P组间=0.036,P交互=0.001),其中治疗后1、2、3周时A、B组PI均低于C组,差异有统计学意义(P<0.05),A、B两组间差异无统计学意义(P>0.05)。A组和B组患儿治疗后PI呈下降趋势,C组治疗后1周时降低后逐渐升高。3组患儿不良反应发生率(A组2/40,B组3/40,C组0/40)比较,差异无统计学意义(χ2=2.922,P=0.232)。结论柠檬提取物漱口液与复方醋酸氯己定漱口液效果相当,对儿童牙菌斑有抑制和治疗作用,安全性较好。Objective To analyze the effect of lemon peel extract mouth rinses on children＇s dental plaques. Methods A total of 120 children with dental caries aged 5- 8 years who visited Tianjin Children＇s Hospital from March 2011 to March2013 were divided randomly into groups A,B,C,40 in each. Group A were given lemon peel extract mouth rinse,group B given compound chlorhexidine acetate mouthwash,group C given pure water. Dental plaque index（ PI） and adverse reactions related to the treatments were recorded before treatment and in weeks 1,2,3 after treatment. Results There was significant difference in PI among 3 groups before treatment and in weeks 1,2,3 after treatment（ Ftime= 21. 670,Fgroup= 3. 430,Ftotal=7. 329; Ptime= 0. 001,Pgroup= 0. 036,Ptotal= 0. 001）,there was significant difference in groups A,B and group C,but no difference between group A and B. PI decreased in groups A,B after treatment,reduced at first and then increased gradually in group C in week 1 after treatment. There was no difference in incidence of adverse reaction among 3 groups（ 2 /40 in group A,3 /40 in group B,0 /40 in group C; χ2= 2. 922,P = 0. 232）. Conclusion Lemon peel extract mouth rinse and compound chlorhexidine acetate mouthwash effect well on child dental plaques with good safety.

关 键 词：柠檬 植物提取物 牙菌斑 龋齿 

分 类 号：R788.1[医药卫生—口腔医学]