壳聚糖的改性及其自由基清除性能  

Modification of Chitosan and Free Radical Scavenging Activities

作　　者：周元敬 徐青 赵红霞[3] 高贵龙[4] 

机构地区：[1]贵州省分析测试研究院,贵阳550002 [2]贵州省生物研究所,贵阳550009 [3]贵阳医学院附属临床医院康复科,贵阳550004 [4]贵州科学院,贵阳550001

出　　处：《上海交通大学学报》2014年第11期1613-1620,共8页Journal of Shanghai Jiaotong University

基　　金：贵州科学院青年基金重点项目(黔科院J合字[2014]01号)资助

摘　　要：介绍了不同相对分子质量、不同脱乙酰化度和O-改性壳聚糖的制备方法,综述了壳聚糖清除自由基性能的研究进展.总结了相对分子质量、脱乙酰度和O-修饰等因素对壳聚糖及其衍生物清除自由基的影响.Chitosan and its derivatives are unique cationic copolymer of glucosamine and N-acetyl-glucosamine. They have drawn much attention in various fields, including pharmaceutical, biomedicine, water treatment, cosmetics, agriculture, and food industry, due to their useful characteristics such as biorenewabilty, biodegradability, biocompatibility, bioadhesivity and nontoxicity. This paper introduced the synthetic method of different molecular weight, different degree of deacetylation and O-modified chitosan. Moreover, it revewed the recent free radical scavenging activities of chitosan and its derivatives and discussed in brief the roles molecular weight, degree of deacetylation and O-modification played in free radical scavenging.

关 键 词：壳聚糖 制备方法 改性 自由基清除 

分 类 号：O636[理学—高分子化学]