胸腺瘤患者术后生存影响因素分析  

Analysis on Influencing Factors of Postoperative Survival in Patients with Thymoma

作　　者：张晓飞[1] 杨康[1] 苏先旭[1] 

机构地区：[1]都江堰市人民医院胸外科,四川都江堰611800

出　　处：《医学综述》2014年第24期4588-4590,共3页Medical Recapitulate

摘　　要：目的探讨影响胸腺瘤患者术后生存率的相关因素。方法对1998年4月至2008年5月在都江堰市人民医院进行手术的67例胸腺瘤患者临床资料进行回顾性分析,分别用Log-rank法和Cox比例风险模型对可能影响胸腺瘤患者术后生存率的因素进行单因素及多因素分析。结果本组患者的1、5、10年生存率分别为92.5%、83.6%、67.2%;单因素分析显示性别、年龄、Masaoka分期、手术方式、WHO组织学分类对胸腺瘤患者术后的生存率有显著影响(P<0.05);多因素分析表明:年龄、Masaoka分期、手术方式是影响胸腺瘤患者术后生存率的独立影响因素。结论胸腺瘤患者的5年内生存率较高,患者的年龄、Masaoka分期、手术方式与其生存率有密切联系。Objective To investigate the influencing factors of postoperative survival rate in patient with thymoma. Methods Clinical data of 67 patients with thymoma admitted in Dujiangyan Municipal Pee ple＇s Hospital from Apr. 1998 to May 2008 were retrospectively analyzed. The possible influencing factors c postoperative survival rate were analyzed by univariate analysis and multivariate analysis with Log-rank an, Cox proportional hazard model. Results Survival rates at the 1^st ,5^th, 10^th year after operation were 92.5% 83.5% ,67. 2%, respectively. Results of univariate analysis showed gender, age, Masaoka staging, surgial approach and WHO histologie classification had significant influence on the postoperative survival rate c patients with thymoma（ P 〈 0.05 ）. Results of multivariate analysis showed that age, Masaoka staging and surgical approach were the independent influencing factors of postoperative survival rate of patients with thy morns. Conclusion Survival rate of patients with thymoma within 5 years after operation is high. The patier gender. Masaoka staging, surgical approach are closely linked to the survival rate of oatients with thymoma.

关 键 词：胸腺瘤 生存率 影响因素 

分 类 号：R736[医药卫生—肿瘤]