健脾肠宁汤加减防治急性放射性肠炎的临床研究  

Clinical Research on the Application of Spleen Chang Ning Fang Decoction for Prevention of Acute Radiation Enteritis

作　　者：杨文娟[1] 王良花[1] 戴安伟[1] 

机构地区：[1]南京中医药大学附属昆山市中医医院,江苏昆山215300

出　　处：《中国中医急症》2014年第12期2277-2279,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：昆山市社会发展项目(KS2011652)

摘　　要：目的观察健脾肠宁汤加减治疗急性放射性肠炎的临床效果。方法选取急性放射性肠炎患者147例,随机分为两组。对照组患者71例,给予氧氟沙星和蒙脱石散口服;观察组患者76例,给予健脾肠宁汤加减治疗,疗程均为14 d。对两组患者治疗效果进行评价,并于治疗前后行中医症状评分。结果观察组患者痊愈率及总有效率分别为22.37%、73.68%,均高于对照组之7.04%、30.99%(P<0.05);观察组患者治疗后中医症状腹痛、腹泻、黏液脓血便、里急后重以及乏力症状评分改善均优于对照组(P<0.05)。结论健脾肠宁汤治疗急性放射性肠炎具有良好的临床效果,可以有效改善患者症状。Objective：To investigate the clinical effects of spleen ChangNingFang decoction in the treatment of acute radiation enteritis.Methods：147 cases of acute radiation enteritis patients were randomly divided into two groups,making it comparable.71 cases in the control group of patients were given oral ofloxacin and montmorillonite powder,while the observation group with 76 cases were given spleen ChangNingFang Decoction.The therapeutic effects of two groups was evaluated,and the TCM symptoms of two groups were scored before and after treatment.Results：The cure rate 22.37％ and effective rate 73.68％ of patients in the observation group were significantly higher than the control group with 7.04％ and 30.99％ ;after treatment,clinical symptoms in the both groups of patients abdominal pain,diarrhea,mucus pus,tenesmus and fatigue symptom scores were improved.Each symptom scores of patients in the observation group were significantly lower than those of the control group.The difference was statistically significant（P＜0.05）.Conclusion：Spleen ChangNingFang Decoction has a good clinical effect on acute radiation enteritis and can effectively improve symptoms,so it is an effective method of treatment.

关 键 词：健脾肠宁汤 预防 治疗 放射性肠炎 

分 类 号：R730.59[医药卫生—肿瘤]