BACE联合I^(125)粒子植入治疗晚期肺癌的临床疗效  

Clinical effect of BACE combined with I^(125) seed in the treatment of patients with advanced lung cancer

作　　者：徐仁良[1] 华双一[1] 查清[1] 支海明[1] 余龙伍[1] 严雄[1] 吴彬彬[1] 

机构地区：[1]中国人民解放军海军安庆医院放射介入科,安徽安庆246003

出　　处：《临床肺科杂志》2015年第2期242-244,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨支气管动脉栓塞化疗(BACE)联合I125植入治疗晚期肺癌的临床疗效。方法选择39例经BACE治疗后支气管动脉闭塞,再次于30天左右联合CT引导下经皮穿刺植入I125粒子治疗,41例BACE治疗作为对照组。结果本组CR17例,PR19例,NC 3例,总有效率(CR+PR)为92.3%。3个月生存率94.2%,6个月生存率91.3%,一年生存率83.2%。对照组CR12例,PR21例,NC 8例,总有效率(CR+PR)80.4%,3个月生存率93.1%,6个月生存率88.4%,一年生存率72.6%。结论 BACE联合CT引导下经皮穿刺植入I125粒子治疗晚期肺癌微创安全,较单纯BACE治疗近中期疗效明显提高,晚期肺癌BACE联合I125综合治疗值得临床推广。Objective To observe the clinical effect of bronchial artery occlusion induced by BACE com-bined with I^125 seed implantation in the treatment of advanced lung cancer.Methods 39 cases of bronchial artery occlusion after BACE treatment were selected,and they were implanted with I^125 seed again in 30 days under CT guided percutaneous.Another 41 cases of BACE were treated as the control group.Results There were 17 cases of CR,19 cases of PR,and 3 cases of NC in the study group.The total response rate （CR＋PR）was 92.3% in the study group. The 3-month survival rate was 94.2%,the 6-month survival rate was 91.3%,and the 1-year survival rate was 83.2% in the study group.There were 12 cases of CR,21 cases of PR,and 8 cases of NC in the control group. The total response rate （CR＋PR）was 80.4%in the control group.The 3-month survival rate was 93.1%, the 6-month survival rate was 88.4%,and the 1-year survival rate was 72.6% in the control group.Conclusion BACE combined with I^125 seed implantation under CT guided percutaneous is minimally invasive safe and shows higher total effective rate in the treatment of advanced lung cancer.

关 键 词：支气管动脉 栓塞 粒子 介入性 

分 类 号：R734.2[医药卫生—肿瘤]