回医烙灸疗法配合护理干预对类风湿性关节炎患者疼痛及血清IL-2、TNF-α水平影响的研究  

Study in influence of Hui medicine flatiron moxibustion therapy and nursing intervention on pain and serum IL-2, TNF-α of RA patients

作　　者：魏雪红[1] 鲁亚玲[1] 段梅欣[1] 武永利[1] 许建峰[1] 

机构地区：[1]宁夏医科大学总医院中医骨伤科,银川750004

出　　处：《中国实用护理杂志》2014年第34期5-8,共4页Chinese Journal of Practical Nursing

基　　金：2012年国家自然科学基金项目（81260545）;2013年国家自然科学基金项目（81360567）

摘　　要：目的 探讨回医特色烙灸疗法配合护理干预对类风湿性关节炎（RA）患者疼痛及治疗前后血清IL-2和TNF-α的影响.方法 选取宁夏医科大学总医院中医骨伤科201 1年5月至2013年9月RA住院患者89例,随机分为对照组43例与治疗组46例.2组患者取穴均采用整体与局部相结合的方法,其中对照组由医生采用温针疗法,30 min/次,1次、d,常规护理;治疗组由专职中医护士采用回医铁质灸具,直接灸腧穴部位,以局部皮肤微微发红为度,30 min/次,1次、d,并在常规护理基础上,重点结合说理开导、情感相胜、暗示转移、定志安神等中医心理护理指导.均10次为1个疗程,疗程间休息3～5 d,3个疗程后进行疗效评价.同时,应用数字疼痛评分法等级量表（NPRS）评估2组患者治疗前后疼痛程度;采用心理健康测试量表（症状自评量表SCL-90）评定2组患者治疗前后心理情绪状况,应用放免法测定2组患者治疗前后血清IL-2和TNF-α含量.结果 治疗组总有效率为89.13％,对照组为74.42％,2组间比较,差异有统计学意义;2组治疗后NPRS、SCL-90评分较治疗前均有明显改善,差异有统计学意义;2组治疗后NPRS、SCL-90评分比较治疗组优于对照组,差异有统计学意义.2组治疗后血清IL-2和TNF-α水平较治疗前均有明显改善,差异有统计学意义;2组治疗后IL-2和TNF-α水平比较治疗组优于对照组,差异有统计学意义.结论 回医烙灸疗法配合中医心理护理干预措施可以有效改善RA患者的疼痛状况,缓解心理焦虑,提高血清IL-2、TNF-α水平,提升患者生活质量,促进病症康复.Objective To investigate the influence of Hui medicine flatiron moxibustion therapy and nursing intervention on pain and serum IL-2,TNF-α in rheumatoid arthritis （RA） patients before and after treatment and care interventions.Methods 89 cases RA hospitalized patients from Traditional Chinese Orthopedics and Traumatology department of General Hospital of Ningxia Medical University were collected and were randomly divided into the control group （43 cases） and the treatment group （46 cases） from May 2011 to September 2013.Two groups used a combination method of overall and portion acupoints.The control group used warm acupuncture,30 min every time,1 time per day,routine care was given.The treatment group was given with Hui medicine flatiron moxibustion instrument by the professional Chinese medicine nurses,direct moxibustion acupoints site to portion skin slight degree redness,30 min every time,1 time per day,and with routine care,focused on the reasons things out the enlighten,emotion,suggested transferring,calm the nerves of the traditional Chinese medicine psychological care guidance.10 times as a course,to rest for 3～5 days on treatment interval,for efficacy evaluation after three courses.Meanwhile,before and after the application,to test the pain degree with NPRS; to assess the psychological and emotional status with SCL-90,serum IL-2 and TNF-α levels were tested with radioimmunoassay.Results The total effective rate was 89.13% on the treatment group,the control group was 74.42%.After treatment,the NPRS,SCL-90 scores were significantly improved than those before treatment; the NPRS,SCL-90 scores of the treatment group were better than those of the control group.After treatment,serum IL-2 and TNF-α levels were significantly improved compared with those before treatment; after treatment,IL-2 and TNF-α levels of the treatment group were better than those of the control group.All the above comparison had statistical significance.Conclusions Hui medicine flatiron moxibustion therapy and nursing int

关 键 词：类风湿性关节炎 回医烙灸疗法 护理干预 白介素-2 肿瘤坏死因子-α INTERLEUKIN-2 Tumor necrosis factor-α 

分 类 号：R248.1[医药卫生—中医临床基础]