云南高校图书馆联盟文献共享服务平台- INTERLEUKIN-2

INTERLEUKIN-2: 作品数：154被引量：351H指数：9; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：鲁亚玲许建峰段梅欣武永利魏雪红更多>>; 相关机构：北京中医药大学中国科学技术大学中国科学院上海生命科学研究院宁夏医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家科技重大专项更多>>

Low-dose interleukin-2 for the treatment of systemic lupus erythematosus with recurrent rash: 《Rheumatology & Autoimmunity》2024年第4期265-266,共2页Jirong Cheng Miao He Di Ma Xing Li Yuanhong Peng; supported by a grant from the Municipal School Cooperative Research Special Project(Sichuan North Medical College)in Nanchong,Sichuan Province,Grant/Award Number:19SXHZ0140.; To the Editor,Systemic lupus erythematosus(SLE)is a chronic autoimmune disease characterized by the production of autoantibodies against self-antigens,leading to widespread inflammation and multi-organ involvement.It ...; 关键词：LUPUS ERYTHEMATOSUS TREATMENT

Evaluating the role of interleukin-2 and interleukin-12 in pediatric patients with concurrent Mycoplasma pneumoniae and Epstein-Barr virus infections: 《World Journal of Clinical Cases》2024年第23期5346-5353,共8页Yan-Ping Hao; BACKGROUND Mycoplasma pneumoniae(MP)frequently causes respiratory infections in children,whereas Epstein-Barr virus(EBV)typically presents subclinical manifestations in immunocompetent pediatric populations.The incide...; 关键词：INTERLEUKIN-2 INTERLEUKIN-12 Mycoplasma pneumonia Epstein-Barr virus COINFECTION

Optimized RNA interference therapeutics combined with interleukin-2 mRNA for treating hepatitis B virus infection被引量：1: 《Signal Transduction and Targeted Therapy》2024年第7期3063-3076,共14页Wenjing Zai Min Yang Kuan Jiang Juan Guan Huijing Wang Kongying Hu Chao Huang Jieliang Chen Wei Fu Changyou Zhan Zhenghong Yuan; supported by the grants from the National Key R&D Program of China(2023YFC2308603,2022YFA1303600,and 2021YFC2300600);the CAMS Innovation Fund for Medical Sciences(2019-12M-5-040);the National Natural Science Foundation of China(82125035,91842309,and 82302505);the Shanghai Education Commission Major Project(2021-01-07-00-07-E00081);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(2017BT01S131);the Shanghai Sailing Program(22YF1409200);the China Postdoctoral Science Foundation(2022M710744).; This study aimed to develop a pan-genotypic and multifunctional small interfering RNA(siRNA)against hepatitis B virus(HBV)with an efficient delivery system for treating chronic hepatitis B(CHB),and explore combined RN...; 关键词：FORMULATION enable offering

Role of IL-2-inducible T-cell kinase in anti-HBV type I interferon expression and anti-HBV activity: 《感染控制(英文)》2024年第2期38-45,共8页Mengxin Lin Jiangfu Liu Zhijun Su Yingying Xu Xiuhua He Ruyi Guo; supported by Quanzhou City Science&Technology Program of China 455(2022NS056);the Science and Technology Department of Fujian Province(No.2024J01121794).; Objective The study aims to investigate the effects of interleukin-2-inducible T-cell kinase(ITK)on hepatitis B virus(HBV)-induced type I interferon(IFN)expression and the antiviral response.Methods Expression of ITK ...; 关键词：hepatitis B virus interleukin-2-inducible T-cell kinase type I interferon

Enzyme-free photothermally amplified fluorescent immunosorbent assay(PAFISA)for sensitive cytokine quantification: 《Aggregate》2023年第6期137-145,共9页Dian Li Wei He Xuyan Lin Xiaodong Cui Stefan Nagl Angela Ruohao Wu Ryan T.K.Kwok Renhua Wu Ben Zhong Tang; Basic and Applied Basic Research Foundation of Guangdong Province,Grant/Award Number:2023A1515010702;National Natural Science Foundation of China,Grant/Award Numbers:31870981,82020108016;Innovation and Technology Commission,Grant/Award Number:ITC-CNERC14SC01;Research Grants Council,University Grants Committee,Grant/Award Numbers:16306620,GRF 16209820;STU Scientific Research Initiation Grant,Grant/Award Number:NTF22023。; Cytokine monitoring has attracted great attention due to its significance in the diagnosis and treatment of many diseases,such as tumors,microbial infections,and immunological diseases.Enzyme-linked immunosorbent assa...; 关键词：cytokine quantitation enzyme free fluorescence intensity ratio metric INTERLEUKIN-2 microchip microscopic mapping photothermally amplified fluorescent immunosorbent assay

Profiles of interferon-gamma and interleukin-2 in patients after allogeneic hematopoietic stem cell transplantation: 《World Journal of Biological Chemistry》2022年第4期72-82,共11页Malwina Rybicka-Ramos Mirosław Markiewicz Aleksandra Suszka-Świtek Ryszard Wiaderkiewicz Sylwia Mizia Monika Dzierżak-Mietła Krzysztof Białas; BACKGROUND Allogeneic hematopoietic stem cell transplantation(allo-HSCT)may be related to the occurrence of complications,including graft-versus-host disease(GvHD)and infections.The pathogenesis of acute GvHD is conne...; 关键词：INTERLEUKIN-2 INTERFERON-GAMMA Cytokine profiles Acute myeloid leukemia Allogeneic hematopoietic stem cell transplantation Acute graft-versus-host disease

Reduction of serum level of interleukin-2 and pruritus severity after acupuncture at Quchi(LI11)in hemodialysis patients:a placebo-controlled randomized clinical trial: 《Journal of Acupuncture and Tuina Science》2022年第2期126-133,共8页Dedi ARDINATA Rozaimah ZAIN-HAMID Irma D MAHADI Hasan MIHARDJA; Objective To observe the effect of acupuncture at Quchi(LI11)on the serum interleukin-2(IL-2)level and the severity of uremic pruritus(UP)in hemodialysis patients.Methods Sixty hemodialysis patients with UP were rando...; 关键词：Acupuncture Therapy Point Quchi (LI11) INTERLEUKIN-2 Pain PRURITUS HEMODIALYSIS Randomized Controlled Trial

Efficacy and safety of low-dose interleukin-2 in combination with methotrexate in patients with active rheumatoid arthritis:a randomized,double-blind,placebo-controlled phase 2 trial被引量：15: 《Signal Transduction and Targeted Therapy》2022年第4期1194-1201,共8页Xiaoying Zhang Miao Miao Ruijun Zhang Xu Liu Xiaozhen Zhao Miao Shao Tian Liu Yuebo Jin Jiali Chen Huixin Liu Xia Zhang Yun Li Yunshan Zhou Yue Yang Ru Li Haihong Yao Yanying Liu Chun Li Yuhui Li Limin Ren Yin Su Xiaolin Sun Jing He Zhanguo Li; National Natural Science Foundation of China(U1903210,31530020,81701598,31570880,81471601,81801617);Beijing SciTech Program(Z171100000417007,Z191100006619114);Macao Science and Technology Fund(0094/2018/A3).; Rheumatoid arthritis(RA)is an aggressive autoimmune arthritis,and current therapies remain unsatisfactory due to low remission rate and substantially adverse effects.Low-dose interleukin-2(Ld-IL2)is potentially a ther...; 关键词：PATIENTS PLACEBO METHOTREXATE

Revealing Functional Significance of Interleukin-2 Glycopro-teoforms Enabled by Expressed Serine Ligation被引量：5: 《Chinese Journal of Chemistry》2022年第7期787-793,共7页Jie Zhao Jiazhi Liu Xinnan Liu Qi Cao Hongbo Zhao Lizhen Liu Farong Ye Can Wang Hong Shao Dongxiang Xue Houchao Tao Bin Li Biao Yu Ping Wang; supported by the National Natural Science Foundation of China(22077080,21907064 and 22107068);Special Projects of the Central Government in Guidance of Local Science and Technology Development(2021Szvup077).; Naturally occurring interleukin-2(IL-2)is a pleiotropic glycoprotein that regulates immune responses by controlling the differentia-tion and homeostasis of T cells.Non-glycosylated IL-2 has been used in clinical setti...; 关键词：OLIGOSACCHARIDE GLYCOPROTEIN Serine ligation INTERLEUKIN-2 GLYCOPEPTIDES

Final results of a 2:1 control-case observational study using interferon beta and interleukin-2,in addition to first-line hormone therapy,in estrogen receptor-positive,endocrine-responsive metastatic breast cancer patients: 《Journal of Cancer Metastasis and Treatment》2022年第1期54-66,共13页Andrea Nicolini Giuseppe Rossi Paola Ferrari Riccardo Morganti Angelo Carpi; Aim:We conducted a pilot study that combines immunotherapy(cyclic interleukin-2 interferon-beta sequence)and hormone therapy(HT)to overcome endocrine resistance in metastatic breast cancer.Methods:The final results of...; 关键词：Breast cancer metastasis HORMONE-DEPENDENT hormone resistance IMMUNOTHERAPY

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