近30年重症肌无力中医证型和用药规律分析  

Analysis on TCM Syndrome Types and Prescription of Myasthenia Gravis in Recent 30 Years

作　　者：双晓萍[1,2] 谭子虎[3] 

机构地区：[1]湖北中医药大学,湖北武汉430061 [2]襄阳市中医院,湖北襄阳441000 [3]湖北省中医院,湖北武汉430061

出　　处：《辽宁中医药大学学报》2015年第1期149-151,共3页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:对1982年1月—2013年12月中国期刊数据库(CNKI)收录的中医治疗重症肌无力文献,通过频次分析,总结既往文献中医治疗的辨证分型及用药规律,为临床治疗、科学研究等提供参考。方法:对所选文献中的证型、方剂和药物进行统计归类,将数据整理后应用spss统计软件进行频数分析、主成分分析、关联规则分析,总结既往文献中中医证型和用药规律。结果:数据库中在全文或摘要字段中含"中医""重症肌无力""痿病"的183篇文献收集有效文献169篇,通过频数分析可见:重症肌无力证型9个,脾胃亏虚、脾虚夹湿、脾肾两虚为常见证型,占76.92%。经方或方名53个,补益剂、祛湿剂占79.24%。统计单味中药134种,黄芪、白术、熟地、山药、升麻、柴胡、淫羊藿等出现频次较高。结论:中医药治疗重症肌无力以健脾益气、补脾益肾、燥湿利水方药为主,以经方或名方为基础随证加减化裁在中医临床中仍应用较多。Objective ： The literatures on the treatment of myasthenia gravis with Chinese medicine were collected from CNKI date in the rang from January 1982 to December 2013. The syndrome types and prescriptions were summarized through frequency analysis so as to probe into the laws of the treatment of the disease in Chinese medicine and scientific research. Methods ： The types of syndromes, formulae and drugs were analyzed ana classified statistically to observe the use frequency and percentage of every syndrome type, prescription and drug with SPSS statistical software. Results： 169 effective literatures from 183 literatures in CNKI, including Chinese medicine, myasthenia gravis and Weibing in abstract or full text. There were announces through frequency analysis. There were 9 syndrome types in myasthenia gravis in which Spleen deficiency, Qi deficiency with dampness, deficiency of spleen and kidney were common syndromes, occupying 76.92%. There were 53 prescriptions in myasthenia gravis in which tonic prescription and dampclearing prescription were common prescriptions, occupying 79.24%. There were totally 134 kinds of drugs applied. Some medicines such as Astragalus mongholicus, Rhizoma Atractylodis Macrocephalae, Rehmannia, Chinese yam, rhizome, radix bupleuri, Herb of Korean, etc, were in high frequency. Conclusion ： The traditional Chinese medicine in prevention and treatment of myasthenia gravis in tonifying qi and spleen, nourishing spleen and kidney and dehumidificating was effective. Some classical or famous prescriptions were widely used in clinic.

关 键 词：重症肌无力 中医 证型分析 方药分析 

分 类 号：R746.1[医药卫生—神经病学与精神病学]