原发性肺滑膜肉瘤诊断与治疗——附一例报告及文献复习  

Diagnosis and treatment of primary pulmonary synovial sarcoma :report of one case and review of literature

作　　者：胡智[1] 刘单[1] 戴天阳[1] 

机构地区：[1]泸州医学院附属医院胸心外科,四川泸州646000

出　　处：《泸州医学院学报》2014年第6期582-585,共4页Journal of Luzhou Medical College

摘　　要：目的:探讨原发性肺滑膜肉瘤的临床表现、诊断方法和治疗预后,以提高原发性肺滑膜肉瘤(pulmonary synovial sarcoma,PPSS)的诊疗水平。方法 :回顾2014年3月我院收治的1例患者PPSS的临床资料。使用Pub Med、Elsevier Science检索系统,复习2002至2013年10余年国外资料齐全临床案例。结果:手术时间为145 min,术中出血约100 ml,第10 d出院。复习临床资料完整15例,主要临床表现为咳嗽、胸痛、咯血;诊断依靠术后病理、分子遗传学特征。结论:PPSS是一种罕见的恶性病变,诊断依靠免疫组化及SYT-SSX融合基因检测,手术治疗,辅助化疗有价值。Objective： To discuss the clinical features, diagnosis, treatment and prognosis of the primary pulmonary synovial sarcoma（PPSS） in order to improve diagnostic and therapeutic levels for PPSS. Methods：The clinical data of one patient suffering from PPSS treated in our hospital in March 2014 were retrospectively analyzed. Case reports with integral clinical data in recent 10 years literature were reviewed through Pub Med 、Elsevier Science searching system with the keyword of＂primary pulmonary synovial sarcoma＂ or ＂primary synovial sarcoma of the lung＂. Results：Operation successfully completed in 145 min with a blood loss of 100 ml;the patient was discharged from the hospital at the 10 th day. Fifteen cases with integral clinical data were reviewed.The major manifestations were cough, chest pain, haemoptysis.Diagnosis was mainly based on pathology and molecular genetic characteristics. Fourteen patients were cured or remitted after surgical therapy; One patient accepted a biopsy. Conclusion： PPSS is a rare malignant disease,and immunohistochemical and SYT- SSX fusion gene detection are important diagnostic methods. Surgery and adjuvant chemotherapy are significant.

关 键 词：滑膜肉瘤 肺叶切除术 肺癌 

分 类 号：R734.2[医药卫生—肿瘤]