支气管袖状肺叶切除术治疗中央型肺癌的疗效分析  

Efficacy of bronchial sleeve lobectomy(BSL) in treating central-type lung cancer

作　　者：彭国庆[1] 冼磊[2] 

机构地区：[1]广西科技大学第二附属医院外三科,柳州545006 [2]广西医科大学第一附属医院心胸外科,南宁530021

出　　处：《中国癌症防治杂志》2014年第4期399-402,共4页CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT

基　　金：广西自然科学基金资助项目(0542078)

摘　　要：目的探讨支气管袖状肺叶切除术治疗中央型肺癌的疗效。方法收集中央型肺癌行支气管袖状肺叶切除术患者37例(观察组)和行全肺叶切除术患者42例(对照组),对两组患者术中、术后并发症及生活质量、术后1年、3年、5年生存率进行观察和分析。结果观察组及对照组患者术后并发症发生率分别为18.9%和40.5%,观察组患者术后并发症发生率较对照组明显下降(P<0.05)。两组患者术后1年、3年生存率无明显差异,观察组和对照组患者术后5年生存率分别为54.1%和42.9%,两组差异有统计学意义(P<0.05)。观察组患者术后肿瘤复发和肿瘤转移率(分别为27.0%和16.2%)均较对照组(分别为35.7%和21.4%)显著降低(P<0.05)。术后观察组患者各生活质量评分指数均较对照组高(P均<0.05)。结论支气管袖状肺叶切除术较全肺叶切除术可明显降低中央型肺癌患者术后并发症的发生,提高患者术后生活质量和5年生存率。Objective To explore the effectiveness of bronchial sleeve lobectomy （BSL）for treating central-type lung cancer. Methods Complications during and after surgery, quality of life and survival rates at 1,3 and 5 years were retrospectively analyzed in 79 patients with central lung cancer,comprising 37 who underwent bronchial sleeve lobectomy （BSL） and 42 who underwent pneumonectomy. Results Postsurgical complications were significantly less frequent in the BLS group （18.9%） than in the pneumonectomy group （40.5% ;P〈0.05）. Although the two groups presented similar survival rates at 1 and 3 years,the BLS group showed a significantly higher 5-year survival rate （54.1% vs 42.9% ;P〈O.01 ）. The BLS group also showed significantly lower rates of cancer recurrence （27.0% vs 35.7%;P〈0.0） and cancer metastasis （16.2% vs 42.9%;P〈0.01）. The BLS group scored significantly higher on quality of life （P〈0.05）. Conclusion BSL can reduce the complication rate and increase both quality of life and survival after surgery to treat central-type lung cancer.

关 键 词：肺肿瘤 支气管袖状肺叶切除术 全肺叶切除术 疗效 

分 类 号：R734.2[医药卫生—肿瘤]