多形态细支气管肺泡细胞癌64例临床诊治分析  

Clinical analysis of polymorphous bronchioloalveolar carcinoma

作　　者：罗曼[1] 叶媛[1] 王导新[1] 

机构地区：[1]重庆医科大学附属第二医院呼吸内科,重庆400010

出　　处：《西部医学》2015年第1期17-19,共3页Medical Journal of West China

基　　金：国家自然科学基金(81270141)

摘　　要：目的探讨细支气管肺泡细胞癌(bronchioloalveolar carcinoma,BAC)的临床症状、影像学特点、诊断及鉴别诊断要点,以提高临床医生对BAC的诊治水平。方法收集在呼吸内科和胸外科确诊的64例BAC患者临床资料,包括一般资料、临床表现、胸部影像学检查等进行分析总结。结果本组病例男女发病率之比为1.28∶1,平均年龄为61岁,临床表现多为咳嗽、咳痰、胸痛,影像学表现呈多种形态,易被误诊为肺炎、肺结核等,误诊率达50%,综合治疗组较单纯化疗组生存曲线有显著优势,差异有统计学意义(P<0.05)。结论掌握BAC的临床特征、影像学特点、诊断及鉴别诊断要点可减少其误诊率,确诊为BAC的患者均应行基因检测,以制定个性化的治疗方案。Objective To discuss the clinical symptom, imaging feature, key points for diagnosis and differential diagnosis of bronchioloalveolar carcinoma （P, AC）, so as to improve the clinicians diagnosis and treatment of BAC. Methods We collected clinical data of 64 patients with BAC, including general information, clinical manifestation and thoracic image. Results In the enrolled cases, the ratio of male to female is 1.28： 1, average age is 61 years old, clinical features of BAC are cough,expectoration, chest pain, the disease can be easily misdiagnosed as pneumonia or pulmonary tuberculosis, the percentage of misdiagnosed case is 50%. There is statistical difference of survival curve between comprehensive treatment and chemotherapy treatment（P〈0.05）. Conelusion Mastering the clinical feature, imaging feature, key points for diagnosis and differential diagnosis of BAC can reduce the rate of misdiagnosis and mistreatment signifi cantly, genetic test.

关 键 词：细支气管肺泡细胞癌 影像学特征 误诊 分子靶向治疗 

分 类 号：R734.1[医药卫生—肿瘤]