临床拟诊为慢性偏头痛患者硬脑膜静脉窦狭窄程度及其与颅内压的相关性研究  

The Correlation Study between Dural Venous Sinus Stenosis and Intracranial Pressure in Clinical Diagnosed Chronic Migraine by MRV

作　　者：张艳翎 赵建农[1] 邓芬[2] 

机构地区：[1]重庆医科大学附属第二医院放射科,重庆400010 [2]重庆医科大学附属第二医院神经内科,重庆400010

出　　处：《成都医学院学报》2014年第6期699-703,共5页Journal of Chengdu Medical College

摘　　要：目的研究慢性偏头痛患者是否存在大脑静脉窦狭窄、静脉窦狭窄程度与颅内压的相关性,以及窦汇区形态学异常对静脉窦狭窄程度和颅内压的影响。方法运用磁共振静脉成像(MR venography,MRV)技术呈现受试者大脑静脉窦形态学特征;采用静脉窦狭窄程度评分(combined conduit score,CCS)评价111例病例组受试者与66例对照组受试者左右侧横窦、乙状窦及颈内静脉的狭窄程度及111例慢性偏头痛患者窦汇区汇合情况;对病例组受试者行腰椎穿刺术,测量并记录其颅内压水平。结果病例组CCS(7.47±2.71)与对照组CCS(10.18±1.90)比较差异有统计学意义(P<0.05);病例组CCS与其颅内压水平具有高度线性负相关性(R=-0.849,P<0.05);病例组中窦汇异常组CCS(t=-12.524)与非窦汇异常组CCS比较差异有统计学意义(P<0.05)。结论临床拟诊的慢性偏头痛患者多存在硬脑膜静脉窦狭窄,且静脉窦狭窄程度越严重者其颅内压升高越明显;慢性偏头痛患者中窦汇异常者的静脉窦狭窄程度较非窦汇异常者严重,且颅内压水平较非窦汇异常者明显增高。Objective To evaluate whether the dural venous sinus stenosis existed in the patients with chronic migraine or not,the correlation between the degree of dural venous sinus stenosis and the intracranial pressure in Chronic Migraine by MRV and the effect of the abnormal morphology of cranial sinuses on venous sinus stenosis and intracranial pressure in Chronic Migraine.Methods 1）To perform the morphological characteristics of cerebral venous sinus by the MRV;2）To assess the stenosis of the bilateral transverse,sigmoid sinuses and internal jugular veins in the observation group of 111 cases with chronic migraine and the control group of 66 cases and the comprehensive conditions of the 111cases＇ torcular region by CCS;3）To measure and record the datum of the intracranial pressure according to the lumbar puncture in the observation group.Results 1）The CCS scores of dural venous sinus stenosis in the two groups were（7.47±2.71）and（10.18±1.90）respectively（P〈0.05）;2）The degree of dural venous sinus stenosis and the intracranial pressure had a high negative linear correlation（R=-0.849,P0.05）;3）The degree scores of CCS in the patients with normal and abnormal（t=-12.524）torcular region had shown statistically significant difference（P〈0.05）.Conclusion The dural venous sinus stenosis exists in the many patients with clinical diagnosed chronic migraine.As it shown,the more serious the degree of dural venous sinus stenosis is,the higher intracranial pressure is.What＇s more,the patients with abnormal torcular Herophili region have a more severe degree of the dural venous sinus stenosis than the patients with normal torcular Herophili region,and so is the intracranial pressure.

关 键 词：慢性偏头痛 硬脑膜静脉窦狭窄 磁共振静脉成像 窦汇 

分 类 号：R743.9[医药卫生—神经病学与精神病学]