中国青少年罹患流行性癔症人群分布的Meta分析  

Meta analysis of population distribution of epidemic hysteriain children and adolescents in China

作　　者：程庆林[1,2] 谢立[2] 徐勇[1] 

机构地区：[1]苏州大学医学部公共卫生学院儿少卫生教研室,江苏215123 [2]杭州市疾病预防控制中心

出　　处：《中国学校卫生》2014年第11期1610-1615,共6页Chinese Journal of School Health

基　　金：卫生部卫生行为科研专项项目(201202010)

摘　　要：目的分析青少年罹患流行性癔症的人群学特征,为建立青少年流行性癔症评估体系提供科学依据。方法在Pub Med、中国期刊全文数据库（CJFD）等数据库检索青少年流行性癔症相关文献,通过描述性分析和Meta分析的方法评估中国青少年流行性癔症罹患率和流行病学特征,根据异质性检验结果选择模型,罹患率的计算采用纳入各研究罹患率组合加权法。结果 74项研究（n=35 476）被纳入Meta分析,4 927名青少年罹患流行性癔症,52项研究文献质量评估中上等。中国青少年流行性癔症总罹患率为20.5%（95%CI=0.158-0.257,P〈0.01）,青少年流行性癔症人群分布罹患率范围为4.1%-36.7%;男、女性流行性癔病的罹患率分别为10.1%（95%CI=6.4%-15.5%,P〈0.01）和24.6%（95%CI=16.7%-34.8%,P〈0.01）。女性青少年流行性癔症罹患风险是男性青少年的2.99倍（95%CI=2.214-4.035,P〈0.01）。结论中国青少年罹患流行性癔症可能与性别、民族、教育状况、触发因子和不同性别首发病例等因素有关。Objective To synthetically assess population features when children and adolescents encountered epidemic hysteria （ EH）, and to provide bases for designing assessments of epidemic hysteria in children and teenagers. Methods PubMed, China Academic Literature Full-text Database, and other databases and published references were used to identify studies that reported the attack rates of epidemic hysteria in children and teenagers in China. Descriptive epidemiology and meta-analysis were used to assess attack rates. Attack rates were calculated as the aggregate means weighted by the combined number of subjects in the included studies. Results Seventy-four studies （ n = 35 476 ） reporting attack rates of EH in children and teenagers were found in China. In total, the meta-analysis incorporated data on ARs from 4 927 children and adolescents with a history of epidemic hysteria. Fifty-two studies had a high to moderate methodological quality. The pooled attack rate was 20.5%（ 95%CI=0. 158-0.257,P〈 0.01 ）for major epidemic hysteria in children and adolescents in China. Population features ranged from 4.1% to 36.7% for major epidemic hysteria in children and adolescents in China, and the attack rate in females was 2.99 （95%CI= 2.214-4.035 ,P= 0.007） times higher than in males. Conclusion This meta-analysis indicates that population characteristics of epidemic hysteria in Chinese children and adolescents are almost equal to the characteristics found in relevant studies from foreign countries. Hysteria in children and adolescents may be influenced by gender, ethnicity, education status, triggering factors and the index case.

关 键 词：青少年 癔症 META分析 

分 类 号：R195.4[医药卫生—卫生统计学] R749.73[医药卫生—卫生事业管理]