溃疡性结肠炎患者外周血淋巴细胞亚群检测的临床价值  

Clinical Value of Detection of Peripheral Blood Lymphocytes Subgroup of Patients with Ulcerative Colitis

作　　者：武海洲[1] 董瑾[2] 刘淼[1] 雷树红[1] 

机构地区：[1]解放军总医院第一附属医院检验科,北京100048 [2]解放军第306医院检验科,北京100101

出　　处：《标记免疫分析与临床》2014年第6期640-641,648,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：目的探究外周血淋巴细胞亚群检测在溃疡性结肠炎(ulcerative colitis,UC)诊断中的临床价值。方法随机选择解放军总医院第一附属医院2011年1月至2013年12月溃疡性结肠炎确诊患者70例,健康体检人群39人,检测其外周血CD3、CD4、CD8、CD4/CD8四项免疫学指标。以SPSS16.0进行独立样本t检验,分析各项指标的诊断价值。结果溃疡性结肠炎患者与健康人群相比,CD3、CD8差别不明显,CD4、CD4/CD8具有明显差别(P<0.05)。结论淋巴细胞亚群的检测对溃疡性结肠炎实验室诊断具有重要临床价值。Objective To explore the clinical value of detection of peripheral blood lymphocyte subsets （ ulcerative colitis, UC） in the diagnosis of ulcerative colitis. Methods 70 patients diagnosed with ulcerative colitis were randomized collected in this study. The peripheral blood CD3, CD4, CD8 and CD4/CD8 in patients and 39 healthy people were determined. Results Compared with health controls, the CD3 and CD8 in patients had obvious differences, and the CD4 and CD4/CD8 had significant differences （ P 〈 0.05 ）. Conclusion The detection of lymphocyte subsets might have an important clinical value in the diagnosis of ulcerative colitis.

关 键 词：溃疡性结肠炎 淋巴细胞亚群 

分 类 号：R574.62[医药卫生—消化系统]