雷贝拉唑与伊托必利联用方案治疗51例反流性食道炎的临床疗效观察  

The Clinical Curative Effect of Rabeprazole Combined with Itopride in Treatment of Reflux Esophagitis 51 Cases

作　　者：李学良 

机构地区：[1]丹东市宽甸满族自治县中医院内二科,辽宁丹东118200

出　　处：《中国伤残医学》2015年第3期35-36,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：探讨雷贝拉唑与伊托必利联用方案治疗反流性食道炎的临床疗效。方法：选取2012年10月-2013年10月就诊于本院的反流性食道炎患者96例为研究对象，将其随机分为观察组（雷贝拉唑与伊托必利联用组）51例和对照组（雷贝拉唑组）45例，药物治疗8周，然后对2组患者治疗后临床症状评分及胃镜下食管黏膜的变化进行统计及比较。结果：观察组症状评分和胃镜下食管黏膜病变与对照组比，均P＜0．05，存在统计学差异。结论：雷贝拉唑与伊托必利联用方案治疗反流性食道炎的临床疗效确切，值得在临床广泛推广。Objective：To investigate the clinical efficacy of combined regimen in the treatment of reflux esophagitis .Methods：From 2012 October to 2013 October,visit to reflux esophagitis in 96 patients in our hospital as the research object , then they were randomly di-vided into observation group （ rabeprazole combined with itopride group ） 51 cases and control group （ rabeprazole group ） 45 cases, drug treatment for 8 weeks, then the score and gastroscopy the clinical symptoms of 2 patients after the treatment of lower esophageal mucosa were analyzed and compared .Results：In the observation group , symptom score and endoscopic esophageal mucosal changes compared with control group, all P 〈0.05, there was significant difference .Conclusion：The clinical efficacy of itopride hydrochloride combined with rabeprazole in treatment of reflux esophagitis is exact , worth in clinical widely .

关 键 词：雷贝拉唑 伊托必利 反流性食道炎 

分 类 号：R57[医药卫生—消化系统]