康艾注射液联合顺铂方案同步放疗治疗中晚期宫颈癌的临床观察  

Clinical observation on treating terminal cervical cancer by radiotherapy with Kang'ai injection plus cisplatin

作　　者：李向阳[1] 谢小妹[1] 周冲[1] 刘凌[1] 

机构地区：[1]徐州市中心医院,江苏徐州221009

出　　处：《中医临床研究》2014年第34期9-11,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察康艾注射液联合顺铂方案同步放疗治疗中晚期宫颈癌的临床疗效和不良反应。方法:80例中晚期宫颈癌患者随机分为治疗组(康艾注射液联合放化疗组)40例和对照组(单纯放化疗组)40例,评价两组患者放化疗结束后有效率、放化疗期间不良反应及生存质量的改善情况。结果:治疗组有效率优于对照组,但差异无统计学意义(P>0.05)。治疗组不良反应在胃肠道反应、骨髓抑制方面均低于对照组,差异有统计学意义(P<0.05)。治疗组生存质量改善,卡氏评分提高,改善率达到56.3%,两组比较差异有统计学意义(P<0.05)。结论:康艾注射液联合顺铂方案同步放疗治疗中晚期宫颈癌有较好疗效,能有效减轻放化疗的不良反应,提高生存质量。Objective： To observe clinical efficacy and adverse reactions of radiotherapy with Kang＇ai injection plus cisplatin on terminal cervical cancer. Methods： 80 cases were randomly divided into the treatment group and the control group, 40 patients for each. The treatment group was given Kang＇ai injection plus radiotherapy, while the control group was given radiotherapy solo. The total efficiency, side effects and improvement of life quality in two groups were evaluated during and after radiotherapy. Results： The total efficiency in the treatment group was higher than that in the control, but the difference was not statistically significant（P〉0.05）, while side effects in the treatment group such as gastrointestinal tract, bone marrow suppression, feeble and fatigue were significantly lower than those in the control group （P〈0.05）. Kamofsky score were decreased, and the improving rate of life quality in the treatment group was 56.3%, compared with the control group, the difference was statistically significant （P〈0.05）. Conclusion： Radiotherapy with Kang＇ai injection plus cisplatin could effectively reduce side effects and improve quality of life with confirmed efficacy.

关 键 词：康艾注射液 放射治疗 化学治疗 宫颈癌 

分 类 号：R73[医药卫生—肿瘤]