口腔颌面部间隙感染的临床分析  

Clinical analysis of oral and maxillofacial space infections

作　　者：曾晓燕[1] 周维[2] 张波[1] 

机构地区：[1]湖北民族学院附属民大医院口腔科,湖北恩施445000 [2]湖北民族学院附属民大医院检验科,湖北恩施445000

出　　处：《中华医院感染学杂志》2015年第2期421-423,共3页Chinese Journal of Nosocomiology

基　　金：湖北省教育厅科技创新基金资助项目(J200529001)

摘　　要：目的探讨口腔颌面部间隙感染的临床特点、治疗方法及治疗效果,为临床诊治提供参考。方法对医院2009年1月-2013年1月收治的68例口腔颌面部间隙感染患者进行临床分析,分析临床特点,观察临床治疗效果,总结治疗方法。结果致病原因主要为牙源性感染,达55.88%,其次分别为腺源性感染、血源性感染、损伤性感染、医源性感染,分别占23.53%、10.29%、7.35%,2.95%;共分离出病原菌68株,排前3位病原菌依次为溶血性链球菌、大肠埃希菌和金黄色葡萄球菌,分别占42.65%、26.47%、22.06%;68例患者均无死亡病例,其中27例显效,39例有效,总有效率为97.06%;术后出现5例酸中毒等并发症,发生率为7.35%,经治疗后得到明显的改善,无败血症、骨髓炎等严重并发症的发生;单间隙感染患者的治疗时间较短,平均为5.1d,多间隙感染患者的治疗时间较长,平均8.9d。结论口腔颌面部间隙感染多为牙源性感染,病情较急,易造成严重危害,在治疗过程中采取全身抗炎治疗、局部病变治疗和支持治疗的综合治疗方法能够有效的提高治疗效果。OBJECTIVE To explore the clinical characteristics of oral and maxillofacial space infections,put forward the treatment measures,and observe the curative effect so as to provide guidance for clinical treatment.METHODS A total of 68 patients with oral and maxillofacial space infections who were treated in the hospital from Jan 2009 to Jan 2013 were enrolled in the study,the clinical characteristics were analyzed,the clinical curative effect was observed,and the treatment measures were put forward.RESULTS Among the patients with oral and maxillofacial space infections,the patients with tooth-borne infections accounted for 55.88%,the patients with adeno-borne infections 23.53%,the patients with blood-borne infections 10.29%,the patients with invasive infections 7.35%,the patients with iatrogenic infections 2.95%.A total of 68 strains of pathogens have been isolated,among which the Streptococcus hemolyticus,Escherichia coli,and Staphylococcus aureus ranked the top three species,accounting for 42.65%,26.47%,and 22.06%,respectively.Of the 68 patients,no case died,27 cases were markedly effective,and 39 cases were effective,with the total effective rate of 97.06%.The complications such as acidosis occurred in 5cases after the surgery with the incidence rate of 7.35% and were significantly improved after the treatment;the severe complications such as sepsis and osteomyelitis did not occur.The mean treatment time of the patients with single space infections was 5.1days,and the mean treatment time of the patients with multiple space infections was 8.9days.CONCLUSIIONS The tooth-borne infection is the predominant type of oral and maxillofacial space infection,the illness condition is severe and tend to lead to serious damage.The systemic anti-inflammatory treatment,local lesion treatment,and supportive treatment can effectively improve the curative effect.

关 键 词：口腔 颌面部 间隙感染 治疗 

分 类 号：R782.3[医药卫生—口腔医学]