尼麦角林治疗脑梗死后抑郁的疗效观察  

Curative effect of nicergoline on depression after cerebral infarction

作　　者：鲍治诚[1] 王万华[1] 夏雪龙[1] 

机构地区：[1]昆山市第一人民医院神经内科,江苏昆山215300

出　　处：《临床医药文献电子杂志》2014年第17期2372-2373,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的观察尼麦角林治疗脑梗死后抑郁的疗效。方法将100例脑梗死后抑郁患者随机分成观察组50人,对照组50人。观察组口服尼麦角林片,对照组口服谷维素片,疗程8周,治疗前后采用汉密尔顿抑郁量表(HAMD)评分,判断疗效并观察不良反应。结果观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论尼麦角林能明显改善脑梗死后抑郁症状。Objective To observe the effect of nicergoline on depression after cerebral infarction.Methods 100 cases of depression after cerebral infarction were randomly divided into two groups.The numbers of treatment group and control group were 50 each.The treatment group took nicergoline tablets for 8 weeks,and the control group took oryzanol tablets for 8 weeks.Before and after treatment,Hamilton＇s Depression Scale（HAMD） was used to estimate the effect and observed the adverse reaction. Results The overall response rate of the treatment group was significantly higher than the control group（P〈0.05）. Conclusion Nicergoline can improve the symptom of depression after cerebral infarction effectively.

关 键 词：尼麦角林 脑梗死 抑郁 

分 类 号：R749.13[医药卫生—神经病学与精神病学]