温通针法对慢性非细菌性前列腺炎大鼠肿瘤坏死因子-α、白细胞介素-6的影响  

The effect of warming-promotion needling on the TNF-α,IL-6 in rats with chronic non-bacterial prostatitis

作　　者：赵耀东[1] 韩豆瑛[2] 

机构地区：[1]甘肃中医学院,甘肃兰州730000 [2]甘肃省康复中心医院,甘肃兰州730000

出　　处：《甘肃中医学院学报》2014年第4期1-3,共3页Journal of Gansu College of Traditional Chinese Medicine

基　　金：国家自然科学基金地区基金项目(81060304);甘肃省自然科学基金项目(1208RJZA248);甘肃省教育厅项目(0906B-03)

摘　　要：目的观察温通针法对慢性非细菌性前列腺炎大鼠血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)含量的影响,探讨温通针法治疗慢性非细菌性前列腺炎的作用机制。方法将60只雄性Wistar大鼠随机分为空白组、模型组、药物组、针刺组4组,每组15只。采用25%消痔灵注射液0.2 mL(每单侧叶注射0.1 mL)注入前列腺背侧叶造模。针刺组采用温通针法治疗,药物组予以前列康混悬液灌胃,均每日治疗1次,共治疗30 d,观察各组大鼠血清中TNF-α及IL-6的水平。结果造模后模型组TNF-α,IL-6水平与空白组比较均显著增高,2组比较差异有高度统计意义(P<0.01);治疗后药物组及针刺组TNF-α,IL-6水平较模型组显著降低,差异有统计意义(P<0.05或P<0.01),且针刺组降低TNF-α及IL-6水平的作用更为显著,与药物组比较差异有统计意义(P<0.05)。结论温通针法治疗慢性非细菌性前列腺炎的机制与降低TNF-α,IL-6含量,调节机体免疫功能有关。Objective To observe the effect of using warming-promotion needling on the TNF-c~, IL-6 in rats with chronic non-bacterial prostatitis and discuss the mechanism of using warming-promotion needling in treating it. Methods 60 male Wistar rats were randomly divided into four groups：normal group, model group, acupuncture group,medicine group, each group has 15 rats. The model was created by injecting 25% Xiaozhiling Injection （0.2 mL） into the mice＇ s lateral lobe of prostate. Except the normal group,the other groups were respectively ad- ministered by corresponding disposal every day for one month. The IL-6 and TNF-α in rat＇ s serum were observed. Results Compared with the normal group, the level of IL-6 and TNF-α were increased markedly in model group, there was a significant difference （P〈0.01）. After treatment, the level of IL-6 and TNF-α decreased obviously in medicine and acupuncture groups,there was a significant difference （ P〈0.05 or P〈0.01 ）. In contrast to medicine group, acupuncture group had much more remarkable descent. Conclusion The mechanism of warming-promotion needling in treating chronic non-bacterial prostatitis is relevant to reduction of TNF-α, IL-6 and regulation of body＇ s immune function.

关 键 词：高速飞行器 天馈设备 方向图可重构 可控波束 导航抗干扰 

分 类 号：R-27[医药卫生]