甲状旁腺癌的研究进展  

Research progress of parathyroid carcinoma

作　　者：刘艳芳[1] 刘建忠[1] 王慎田[1] 

机构地区：[1]潍坊市益都中心医院普外科,山东省262500

出　　处：《中华临床医师杂志（电子版）》2015年第2期95-98,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：甲状旁腺癌是少见的内分泌恶性肿瘤之一,其主要表现是甲状旁腺激素水平升高导致的高血钙症状和由于高钙血症引起的各种代谢紊乱以及相应组织器官的损害。完善的实验室检查、准确的影像学定位和可靠的组织病理学特征是甲状旁腺癌诊断的重要依据。甲状旁腺癌对放疗、化疗不敏感,肿瘤及其周围受侵组织的完整切除是首选的治疗方式。PTH诱导的免疫治疗作为一种新的治疗方法备受关注,预后主要取决于初次手术时肿物的完全切除及术后高钙血症的控制及监测。Parathyroid carcinoma is a rare malignant endocrine tumor, its main performances are high blood calcium symptoms caused by elevated parathyroid hormone （PTH） and the corresponding damage of tissues and organs. Perfect laboratory examinations, the accurate imaging localization and reliable histopathological characteristics are the important basises of parathyroid carcinoma diagnosis. Parathyroid carcinoma is not sensitive to radiation therapy and chemotherapy, complete resection of tumor and its surrounding invaded organizations is the preferred treatment. Immunotherapy induced by PTH as a new method of treatment is paid more attention. Prognosis of the parathyroid carcinoma mainly depends on the complete resection of the tumor in the first operation and the control and the monitoring of hypercalcemia.

关 键 词：甲状旁腺肿瘤 甲状旁腺功能亢进症 研究 

分 类 号：R736.2[医药卫生—肿瘤]