急性脑梗死患者同型半胱氨酸、EGF、VEGF检测的临床意义  

The clinical significance of Hcy, EGF and VEGF detection in patients with acute cerebral infarction

作　　者：李曼[1] 陈正徐[1] 金娟[1] 张白银[1] 俞谦[1] 袁润林[1] 郑元杰[1] 

机构地区：[1]合肥市第二人民医院检验科,安徽合肥230011

出　　处：《医学检验与临床》2014年第6期61-62,93,共3页Medical Laboratory Science and Clinics

摘　　要：目的：探讨急性脑梗死患者血Hcy、EGF、VEGF浓度与疾病严重程度的关系。方法：选择109例急性脑梗死患者为研究对象，同期住院最近无新发脑梗死患者30例为对照组。入院时进行神经功能缺损评分并经CT或MRt测量脑梗死体积，分为大、中、小梗死三组，同时测定被检者血Hcy、EGF、VEGF浓度。结果：急性脑梗死患者血Hcy、VEGF水平明显高于对照组（P〈0．01），EGF水平明显低于对照组（P〈0．01），大、中、小梗死三组血Hcy、EGF、VEGF浓度两两比较均有差异。结论：Hcy、EGF、vEGF联合检测在判断急性脑梗死的损伤程度和预后有较重要的指导价值。Objective ： To explore the relationship between disease severity and Hcy, EGF, VEGF concentrations of patients with acute cerebral infarction. Methods ： A total of 30 healthy persons and 109 acute cerebral infarction patients＇ serum Hcy, EGF and VEGF were detected. Patients with acute cerebral infarction were divided into large, medium and small groups by CT or MRI measurements, and nerve function defect grade on admission.Results ： As for acute cerebral infarction, serum Hcy and VEGF were significantly higher than control groups （ P〈0.01 ） ,but serum EGF was significantly lower than control groups （ P〈0.01 ） .There were significant difference between large, medium and small groups . Conclusions ： Hey, EGF and VEGF joint detection plays an important role in judging the damage degree and prognosis of acute cerebral infarction.

关 键 词：急性脑梗死 HCY EGF VEGF 

分 类 号：R743.33[医药卫生—神经病学与精神病学]