新生淋巴管与角膜移植排斥的研究进展  

Research advances in corneal new born lymphatic vessel and corneal transplantation rejection

作　　者：麦洁英[1] 唐先玲[1] 刘平[1] 

机构地区：[1]哈尔滨医科大学第一附属医院眼科医院,中国黑龙江省哈尔滨市150001

出　　处：《国际眼科杂志》2014年第12期2168-2171,共4页International Eye Science

摘　　要：角膜新生淋巴管构成了角膜免疫反应的传入弧,在免疫反应中发挥了重要作用。由于新生淋巴管的出现破坏了免疫机制使角膜移植术后排斥反应发生率升高。随着淋巴管内皮标记物的相继出现和对淋巴管生成因子的研究深入,众多学者对角膜淋巴管在角膜免疫排斥反应机制、治疗和预防等方面进行了大量研究,通过抑制新生淋巴管提高植片存活率。Corneal newborn lymphatic vessels construct the afferent arc of corneal immunological reaction, which play important role in immune response. The corneal transplantation rejection rate rises due to the emergence of new lymphatic vessel which breaks the immunologic mechanism. With the founding of specific marker of lymphatic endothelial cells and research advancing of growth factor of lymphatic vessels, the mechanism, therapy and prevention of corneal immunological rejection reaction of corneal lymphatic vessel have been studied intensively. The graft survival rate has been greatly improved through inhibiting newborn lymphatic vessel.

关 键 词：角膜新生淋巴管 角膜移植排斥 免疫赦免 

分 类 号：R779.65[医药卫生—眼科]