经肛门切除术治疗直肠癌:保留肛门功能与较差的远期疗效  

Transannal Excision in the Treatment for Rectal Cancer:Inferior Long-term Oncologic Result and Preservation of Sphincter Function

作　　者：叶盛威[1] 

机构地区：[1]湖北省肿瘤医院,湖北武汉430079

出　　处：《肿瘤学杂志》2015年第1期1-4,共4页Journal of Chinese Oncology

摘　　要：对uT1期直肠癌,NCCN指南和卫生部门的规范都推荐应用经肛门切除术治疗,但是文献表明其疗效存在争议。文章综述了经肛门切除术的发展、适应证以及长期疗效,并回顾了经肛门切除术后存在高危因素时的及时补救手术和复发后的挽救手术效果。所有这些结果表明:经肛门切除术适用于某些对经腹部大手术有禁忌证的患者,或者适用于某些对保留肛门意愿极其强烈而不愿做大手术的患者,但是他们必须明白,经肛门切除术治疗直肠癌的疗效低于常规的根治性手术,包括增加癌症相关的死亡风险。Transanal exsicion（TAE） for uT1 rectal cancer is recommended on NCCN guideline and Chinese healthy administration norm,but it is still a controversy on prognosis in the literatures. The progress,indication, and long-term oncologic results of TAE are reviewed, and salvage surgery for patients with high risk factors and local recurrence after TAE are discussed. All results show that：TAE should be restricted to patients with medical contraindications to major abdominal surgery or with strong desire to anal sparing. But they should know that TAE offers significantly inferior oneologic results, including a greater risk of cancer-related death.

关 键 词：直肠肿瘤 经肛门切除术 疗效 

分 类 号：R735.37[医药卫生—肿瘤]