综合治疗在髓外浆细胞瘤中的应用  被引量:2

Application of comprehensive treatment on extramedullary plasmacytoma

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作  者:张继青[1] 钟雷[2] 葛宁[1] 韩栋梁[1] 李伟宏[1] 

机构地区:[1]广州军区武汉总医院放射治疗科,湖北武汉430070 [2]广州军区武汉总医院门诊部,湖北武汉430070

出  处:《广州医科大学学报》2014年第4期143-146,共4页Academic Journal of Guangzhou Medical University

摘  要:目的:探讨髓外浆细胞瘤的临床特点诊疗手段。方法:对1995年1月至2013年12月在本科室收治的18例髓外浆细胞瘤进行回顾性分析,其中单纯放射治疗2例(11.7%),综合治疗15例(83.3%),单纯手术1例(5.6%)。结果:中位随访71个月(5-263个月),2例(11.7%)局部复发,3例(16.7%)转化为多发性骨髓瘤,单纯手术或放射治疗5年生存率为0,综合治疗的3、5、10年生存率分别为83.3%(15/18)、77.8%(7/9)、71.4%、(5/7)。结论:综合治疗髓外浆细胞瘤可获得良好的局部控制率和长期生存率,部分髓外浆细胞瘤可向多发性骨髓瘤转化,故需密切观察。Objective:To investigate the clinical feature and treatment of extramedullary plasmacytoma ( EMP ) . Methods:18 patients with extramedullary plasmacytoma admitted in our hospital from January 1995 to December 2013 were evaluated retrospectively, including 2 cases treated by radiotherapy alone ( 11. 7%) , 15 cases treated by comprehensive treatment ( 83. 3%) , and 1 case by surgery alone ( 5. 6%) . Results: During median follow-up of 71months (5-263moths), 2 (11.7%) developed local recurrences and 3 (16.7%) were converted to multiple mydoma. The survival rate of 5-years surgery alone or radiotherapy was 0. The overall 3, 5, and 10-years survival rates were 83.3% (15/18), 77.8% (7/9) and 71.4% (5/7) respectively. Conclusions:Comprehensive treatment on extramednllary plasmacytoma has good local control rate and long-term survival rate. Part of extramednllary plasmacytoma may convert to multiple myeloma and need close follow-up.

关 键 词:浆细胞瘤/综合治疗 髓外 多发性骨髓瘤 

分 类 号:R730.4[医药卫生—肿瘤]

 

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