角蛋白酶的研究与应用前景  

Recent Advances and Application Prospects in Keratinases

作　　者：杨连[1] 曹永洪 杨培龙[1] 黄火清[1] 

机构地区：[1]中国农业科学院饲料研究所,北京100081 [2]上犹中学,江西赣州341200

出　　处：《生物技术进展》2015年第1期29-34,共6页Current Biotechnology

基　　金：国家科技支撑计划项目(2013BAD10B01)资助

摘　　要：角蛋白酶(keratinase)是一种可以特异性降解角蛋白的酶类,其来源广泛,多种微生物在羽毛降解过程中均可产生角蛋白酶。不同菌种来源的角蛋白酶,其结构、理化性质、活性和底物也不同。其在饲料行业、制革工业和环境废弃物处理等多个方面具有广泛的应用前景,能够产生巨大的社会效益和经济效益。本文系统总结了角蛋白酶的来源、分类、理化性质、作用机理及其在基因工程研究等方面的一些最新进展,简要介绍了其应用研究现状,并展望了角蛋白酶的应用前景。Keratinase is kind of specific enzyme that can degrade keratin. It derives from a wealth of sources. A variety of microorganisms can produce keratinase in the process of feather degradation. Keratinases from different strains are different in structure, physical and chemical properties, activity and also substrate. Keratinase has broad application prospects in feed industry, leather industry, and environmental waste disposal, etc., which bring enormous social and economic benefits. This paper summarizes research progress on keratinase in physicochemieal properties, enzymatic mechanisms, sources and classification, as well as genetic engineering, introduces the status of keratinase application and finally proposes the application prospects.

关 键 词：角蛋白 角蛋白酶 羽毛降解 应用领域 

分 类 号：Q55[生物学—生物化学]