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机构地区:[1]南京医科大学附属苏州医院肿瘤内科,南京215001
出 处:《中国肿瘤临床与康复》2015年第1期9-11,共3页Chinese Journal of Clinical Oncology and Rehabilitation
摘 要:目的探讨高龄肺癌患者预后的影响因素,为高龄肺癌患者的诊断和治疗提供依据。方法回顾性分析98例高龄肺癌患者的临床资料,对患者的性别、功能状态(PS)评分、病理类型、临床分期、是否早期手术、晚期化疗方式以及是否接受放射治疗等因素与生存时间进行单因素分析,对分析结果有统计学意义的因素再进行多因素回归分析。结果 PS评分、临床分期、早期手术和晚期化疗方式与患者的生存时间相关(P<0.05)。多因素回归分析结果显示,PS评分和临床分期是高龄肺癌患者独立的预后危险因素。结论 PS评分和临床分期影响高龄肺癌患者的预后,对PS评分高的患者建议手术治疗,PS评分低的患者建议采取最佳支持治疗。Objective To analysis the influence factors on the prognosis of very elderly patients with lung cancer.Methods 98 very elderly patients with lung cancer were selected,and the risk factors including gender,physical state(PS) score,pathological type,clinical stage,whether or not treated with early surgery,late chemotherapy approach and whether or not received radiotherapy were retrospectively analyzed.Further multivariate analysis on the factors showed statistically significant difference was performed.Results PS score,clinical stage,early surgery,chemotherapy and manner of chemotherapy in later period were related to the survival time(P〈0.05),and PS score and clinical stage are two independent risk factors on the prognosis for elderly patients with lung cancer.Conclusions PS score and clinical stage influence the prognosis of lung cancer in elderly patients,surgical treatment is recommended for patients with high PS score,while the patients with low PS score were recommended to take the best supportive care.
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