不同微创疗法治疗原发性肝癌的近期疗效比较  

Comparision of efficacy of different minimally invasive therapy in the treatment of primary liver cancer

作　　者：郑飞[1] 周文平[1] 

机构地区：[1]沈阳军区总医院肝胆外科,沈阳110840

出　　处：《中国肿瘤临床与康复》2015年第1期53-55,共3页Chinese Journal of Clinical Oncology and Rehabilitation

基　　金：2013年度全军医学科技青年培育项目计划:微创外科技术对于肝胆外科患者免疫功能影响的研究;13QNP004

摘　　要：目的比较不同微创疗法治疗原发性肝癌的近期疗效。方法选取2011年5月至2013年5月间收治的原发性肝癌患者120例,将其随机分为A组、B组和C组,每组40例。其中A组采取射频消融法的微创疗法进行治疗,B组采用氩氦刀冷冻的微创疗法进行治疗,而C组则采用无水酒精注射的微创疗法进行治疗,分析原发性肝癌直径>5 cm以及≤5 cm患者的近期生存率和肿瘤减小率。结果 3种不同微创治疗方法治疗直径≤5 cm的原发性肝癌患者的近期生存率差异无统计学意义(P>0.05)。3种不同微创疗法治疗,直径>5 cm的原发性肝癌患者的近期生存率比较,A组优于B组和C组,差异有统计学意义(P<0.05);B组与C组比较,差异无统计学意义(P>0.05)。B组患者肿瘤减小率要优于A组患者,差异有统计学意义(P<0.05)。结论不同的微创疗法对不能手术切除且直径≤5 cm的原发性肝癌患者的近期生存率无明显差异,而射频消融法治疗直径>5 cm的原发性肝癌患者的近期疗效则十分明显,具有高效、安全的治疗优势,能够有效延长患者的生存期,减少患者痛苦,值得临床推广应用。Objective To Compare of efficacy of different minimally invasive therapy in the treatment of primary liver cancer.Methods From May to 2014 2013 in General Hospital of Shenyang Military Command between May 120 cases of primary liver cancer patients,which were randomly divided into three groups,denoted as A group,B group and C group,respectively 40 cases.Among them,A group adopted radiofrequency ablation and minimally invasive therapy,group B with minimally invasive therapy of argon helium cryoablation in the treatment,while the C group with minimally invasive therapy percutaneous ethanol injection for treatment.After treatment,comparison and analysis of primary hepatocellular carcinoma diameter more than 5 cm and less than 5 cm in patients with recent survival rate and mass reduction rate.Results Three kinds of minimally invasive treatment method for the treatment of diameter of not more than 5 cm in patients with primary liver cancer survival rate has no obvious difference（P〈0.05）.While the C group for the treatment of patients with primary liver cancer is better than that of A group,with statistical significance（P〈0.05）.As for the three kinds of minimally invasive therapy in the treatment of more than 5 cm in diameter of primary carcinoma of the liver in survival rate,A group than in B group and C group,with statistical significance（P〈0.05）,while the B group and C group compared to the short-term survival rate,no significant difference（P〈0.05）.After a period of time,patients in the B group was better than that of mass decreases in the patients of A group,with statistical significance（P〈0.05）.Conclusions According to the different period of primary liver cancer patients,should adopt different minimally invasive therapy.Not operation resection and diameter of not more than 5 cm in patients with primary hepatocellular carcinoma had no obvious difference in survival rate,and radiofrequency ablation for the treatment of minimally invasive therapy with diameter more than 5 cm in hepatocel

关 键 词：微创疗法 原发性肝癌 近期疗效 

分 类 号：R735.7[医药卫生—肿瘤]