乳腺癌患者乳腺外器官可疑恶性病变穿刺活检的临床意义  

Needle biopsy of suspected malignant lesions in patients with breast cancer

作　　者：乔伟[1] 庄一平[1] 马大伟[2] 夏雷[2] 张晋[1] 孙磊[1] 李旸[1] 冯勇[1] 

机构地区：[1]江苏省肿瘤医院影像科,江苏南京210009 [2]江苏省肿瘤医院病理科,江苏南京210009

出　　处：《现代医学》2014年第12期1429-1432,共4页Modern Medical Journal

摘　　要：目的:探讨乳腺癌患者乳腺外器官可疑恶性病变穿刺活检的价值。方法:对35例影像学检查怀疑乳腺外器官有恶性病变的病灶行CT引导下经皮细针穿刺活检术,并分析穿刺活检病理结果及其临床意义。结果:所有病例均一次穿刺成功。35个病灶穿刺明确为恶性30个,穿刺活检阳性预测值为100.0%(30/30),敏感性为85.7%(30/35)。23个活检确诊为腺癌病灶的免疫组化标记分析诊断为肺原发性腺癌5例,转移性乳腺癌14例,无法确定转移或原发4例。在14例转移性乳腺癌病例中,ER、PR及HER-2均为阴性病例3例。结论:乳腺癌患者行乳腺外器官可疑恶性病变穿刺活检是获取病理学确诊依据的有效手段,可以满足临床对病变良恶性定性及恶性病变组织学分型和免疫组化诊断的要求,其安全可靠,值得推广。Objective： To explore the value of needle biopsy on suspected malignant lesions in patients with breast cancer. Methods： Thrity-five patients with breast cancer in which according to the imaging diagnosis malignant lesions in other organs were suspected were carried out CT-guided needle biopsy. The pathology results and clinical value were analyzed in all cases. Results： Biopsy was successful in all cases. Thrity of the 35 cases were diagnosed to be malign. The positive predictive value was 100. 0% （30/30）. The sensitivity was 85.7% （30/35）. Twenty- three cases were diagnosed to be adenocarcinoma by immunohistochemical markers, including 5 primary lung cancers, 14 metastatic breast cancers and 4 unable to be determined. ER, PR and HER-2 statuses were negative in 3 of the 14 metastatic breast cancer cases. Conclusion： The needle biopsy of suspected malignant lesions in patients with breast cancer is an effective method for pathology diagnosis , and it can distinguish malignant lesions, and it can meet the requirements of immunohistochemical method, and it is worth promoting. diagnosis.

关 键 词：乳腺肿瘤 肿瘤转移 CT引导 活组织检查 针吸 

分 类 号：R737.9[医药卫生—肿瘤] R730.49[医药卫生—临床医学]