TPF方案诱导化疗联合同期放化疗治疗中晚期鼻咽癌的近期疗效  

Short-term Therapeutic Effect for Induction Chemotherapy and Concurrent Chemoradiotherapy in Advanced Nasopharyngeal Carcinoma

作　　者：蓝玉宏 

机构地区：[1]广东省惠州市惠州中心医院肿瘤放疗科,广东惠州516002

出　　处：《中国医药指南》2015年第1期30-31,共2页Guide of China Medicine

摘　　要：目的研究分析TPF方案诱导化疗联合同期放化疗治疗中晚期鼻咽癌的近期疗效。方法选取我院2012年4月至2013年4月收治的78例中晚期鼻咽癌患者,随机将其分成对照组与研究组两组,给予对照组采用PF方案同期放化疗,给予研究组在对照组的基础上加用TPF方案诱导化疗2周期,比较两组近期疗效。结果研究组治疗有效率分别为87.2%、82.1%,明显高于对照组的59.0%、53.8%,有统计学意义(P<0.05),研究组患者的血液毒性发生率高于对照组(P<0.05)。结论诱导化疗联合放疗治疗中晚期鼻咽癌,近期疗效佳,耐受性较好。ObjectiveTo study the Short-term therapeutic effect for induction chemotherapy and concurrent chemoradiotherapy in advanced nasopharyngeal carcinoma.Methods From April 2012 and April 2013,78 patients with nasopharyngeal carcinoma（NPC） middle-late period, randomly divided into control group and the team will be two groups, control group only with concurrent chemoradiotherapy treatment, giving the team in the control group with induction chemotherapy method.Results Treatment group effectiveness were 87.2%, 87.2%, significantly higher than the control group were 59.0%, 53.8%, obvious difference compared the two groups was statistically significant（P〈0.05）.Conclusion Induction chemotherapy combined radiotherapy treating middle-late nasopharyngeal carcinoma, the recent curative effect good.

关 键 词：诱导化疗 同期放化疗 鼻咽癌 疗效 

分 类 号：R739.63[医药卫生—肿瘤]