The efficacy of ^(89)Sr combined with ^(99)Tc-MDP in the treatment of the advanced breast cancers with bone metastases  

^(89)锶联合云克治疗晚期乳腺癌骨转移80例疗效观察(英文)

作　　者：Qiuju Lin Wenhui Li 

机构地区：[1]The Second Division, Qingdao Cancer Hospital

出　　处：《The Chinese-German Journal of Clinical Oncology》2014年第12期560-562,共3页中德临床肿瘤学杂志（英文版）

摘　　要：Objective： The aim of our study was to evaluate the efficacy of 89Sr combined with Technetium [^99Tc] Methylene- diphosphonate Injection （^99Tc-MDP） in the treatment of cancer pain in the advanced breast cancers with bone metastases. Methods： A total of 80 patients with various degrees of bone pain due to multiple metastases of breast cancer were treated with ^89Sr combined with ^99Tc-MDP. ^89Sr was given intravenously at 4mCi on day 1 during the 3-month schedule. After 7 days, ^99Tc-MDP was given at 22 rag/day on days 1-10 during the 1-month schedule, for 3 to 6 months. Results： The effective rate of relieving pain was 83.75%. The effective rate of curing bone metastases was 81.25%. So there was a significant improvement in the quality of life of the patients. Conclusion： ^89Sr combined with ^99Tc-MDP are effective in the treatment of cancer pain in the breast cancers with bone metastasis, and can obviously repair the bone destruction caused by metastases, thereby improving the quality of life in advanced breast cancer patients with bone metastases.

关 键 词：breast cancer bone metastases ^99TC-MDP ^89SR 

分 类 号：R737.9[医药卫生—肿瘤]