乳腺癌肉瘤临床病理分析并文献复习  

Clinicopathologic Analysis of Breast Carcinosarcoma: a Literature Review

作　　者：张俊[1] 王晶晶[1] 许春伟[1] 刘翠[1] 张博[1] 邵云[1] 王怀涛[1] 吴永芳[1] 李晓兵[1] 乔西平[1] 

机构地区：[1]军事医学科学院附属医院病理科,北京100071

出　　处：《解放军医药杂志》2015年第1期113-116,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的探讨乳腺癌肉瘤的临床病理学特点及诊断要点。方法对1例乳腺癌肉瘤进行临床资料、病理形态学及免疫组化观察,并结合文献对其诊断及鉴别诊断进行探讨。结果镜下分为癌和软骨肉瘤两种成分,免疫组化结果显示癌部分ER(-),PR(-),Her-2(-),Ki-67(index约80%),Tau(弱+),Top-Ⅱα(+),CK(+),EMA(+),CK5/6(-),CK14(散在+),EGFR(+);软骨肉瘤部分:CK(-),S-100(+),Vimentin(++),CD68(部分+)。结论掌握乳腺癌肉瘤的病理学特点,提高对乳腺癌肉瘤的认识,以避免误诊。Objective To explore the clinicopathologic characteristics and diagnostic criteria of breast carcinosarcoma. Methods Clinical data,pathomorphology and immunohistochemical staining of one patient with breast carcinosarcoma cell tumor were observed,and its diagnosis and differential diagnosis combined with literature were also analyzed. Results Microscopic examination showed that the tumor tissues were composed of cancer and chondrosarcoma.Immunohistochemical staining showed that cancer parts were ER（-）,PR（-）,Her-2（-）,Ki-67（ index about80%）,Tau（ weak ＋）,Top-Ⅱα（ ＋）,CK（ ＋）,EMA（ ＋）,CK5 /6（-）,CK14（ scattered ＋） and EGFR（ ＋）;chondrosarcoma parts were CK（-）,S-100（ ＋）,Vimentin（ ＋ ＋） and CD68（ part ＋）. Conclusion It is essential to grasp the pathological characteristics of breast carcinosarcoma and enhance awareness so as to avoid misdiagnosis.

关 键 词：乳腺肿瘤 病理学 临床 免疫组化 

分 类 号：R737.9[医药卫生—肿瘤]