751例老年消化性溃疡患者的致病危险因素与临床特征  

Risk factors and clinical features of 751 cases of elderly peptic ulcer patients

作　　者：成旭东[1] 

机构地区：[1]徐州市第一人民医院老年科,江苏徐州221002

出　　处：《胃肠病学和肝病学杂志》2014年第12期1482-1485,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨老年消化性溃疡患者的致病危险因素和临床特征。方法选取徐州市第一人民医院2006年2月-2014年5月收治的老年消化性溃疡患者751例和同期治疗的846例中青年消化性溃疡患者,对两组患者消化性溃疡的影响因素、临床表现、并发症及伴发病症、溃疡发生部位和溃疡大小进行回顾性对比分析。结果两组患者的饮酒、抑郁、非甾体抗炎药使用情况之间相比,差异有统计学意义(P<0.05),而抽烟和H.pylori感染差异无统计学意义(P>0.05);老年组消化性溃疡并发的上消化道出血、基础性疾病所占比例显著多于中青年组(P<0.01);老年组患者典型症状发生率为4.53%,显著低于中青年组,差异有显著统计学意义(P<0.01);溃疡主要发生在胃部的老年组患者(63.65%)明显多于中青年组患者(30.26%);溃疡直径≥2 cm的老年患者为11.05%,显著多于中青年组(P<0.01)。结论老年消化性溃疡患者有自身特点,临床表现不够典型,发生部位转移向高位,临床治疗应引起重视。Objective To investigate the disease risk factors and clinical features of elderly peptic ulcer patients. Methods Seven hundred and fifty-one cases of elderly peptic ulcer patients and 846 cases of young patients who were treated in the First People＇ s Hospital of Xuzhou City from Feb. 2006 to May. 2014 were admitted for the study. A retro- spective contrast and analysis was made about the factors, clinical manifestations, concurrent disease and associated dis- orders, the ulcer parts and size between two groups. Results There had statistical difference in drinking, depression, the use of NSAIDs between two groups （P 〈 0.05） , while there had no difference in smoking and infection of H. pylori between two groups （P 〉 O. 05 ） ; the rates of concurrent upper gastrointestinal hemorrhage and associated underlying dis- ease of elderly peptic ulcer showed a significant statistical difference in comparison with the young group （P 〈 0.01 ）. The incidence of typical clinical symptoms was 4.53% in the elderly group, which was obviously lower than that in the young group （P 〈0.01）. The elderly patients with ulcers mainly located in stomach （63.65%） was much more than the young group （30.26%）. The ratio of ulcers ≥2 cm in diameters was 11.05% , which showed a statistical differ- ence compared with the young group （P 〈 0.01 ）. Conclusion The elderly patients with peptic ulcer have their charac- teristics and the clinical symptoms are not typical. The ulcer has transferred to top gastric, which should deserved more attention.

关 键 词：老年消化性溃疡 危险因素 临床表现 

分 类 号：R57[医药卫生—消化系统]