原发性阑尾黏液腺癌的临床病理观察  

Linical and pathological observation of primary appendiceal mucinous adenocarcinoma

作　　者：戴晓晓[1] 杨琴[1] 徐俊[1] 

机构地区：[1]江苏省苏州市吴中人民医院病理科,江苏苏州215128

出　　处：《中国医药科学》2014年第24期96-98,112,共4页China Medicine And Pharmacy

摘　　要：目的探讨原发性阑尾黏液腺癌的临床病理特征。方法对2例原发性阑尾黏液腺癌进行临床、组织学和免疫组化观察,并复习相关文献。结果 2例阑尾黏液腺癌发病年龄均为60岁以上,临床症状酷似慢性阑尾炎。形态学表现为分化好的黏液上皮性病灶,上皮细胞立方或柱状,核位于基底,胞浆透亮,腺腔充满胶冻状黏液。免疫表型:瘤细胞CK(+)、EMA(+)、CK20(+)、Ki-67(+)、CK7(-)、Ch-A(-)、Syn(-)。结论原发性阑尾黏液腺癌是临床少见肿瘤,易被临床医师误诊为阑尾炎,确定原发诊断较困难,根据组织学形态和免疫组化表型可确诊。Objective To study the clinical and pathological features of primary appendiceal mucinous adenocarcinoma. Methods 2 cases of primary appendiceal mucinous adenocarcinoma were observed about histology, immunohisto and chemistry, and reviewed the related literature. Results The age of onset of the appendiceal mucinous adenocarcinoma were both 60 and above, clinical symptoms liked chronic appendicitis. The morphology of the lesions appeared as good differentiation mucinous epithelial, cuboidal or columnar epithelial cells, nuclear was in the basal, cytoplasm was translucent, glandular cavity was filled with jelly mucus. Immunophenotyping：cancer cell CK（＋）, EMA（＋）, CK20（＋）, Ki-67（＋）, CK7（-）, Ch-A（-）, Syn（-）. Conclusion Primary appendix mucinous adenocarcinoma is a rare tumor in clinical, easily by clinicians misdiagnosed as appendicitis, identify the primary diagnosis is difficult, according to the, histological appearance and immunohistochemical phenotype can be diagnosed.

关 键 词：阑尾黏液腺癌 原发性 临床病理特征 

分 类 号：R735.36[医药卫生—肿瘤]