泽漆脂溶性成分的气相色谱-质谱联用分析  

GC-MS Analysis of Liposoluble Contents from Euphorbia helioscopia L.

作　　者：徐晶 张在龙 刘海利[3] 郭跃伟[3] 

机构地区：[1]中国石油大学理学院,山东青岛266580 [2]潍坊生物医药创新创业服务中心,山东潍坊261205 [3]中国科学院上海药物研究所新药研究国家重点实验室,上海201203

出　　处：《时珍国医国药》2015年第1期9-10,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家海洋"863"计划(No.2013AA092902);国家自然科学基金(No.81273430;No.31070310);中科院上海药物研究所新药研究国家重点实验室项目(No.SIMM1203ZZ-03)

摘　　要：目的对泽漆脂溶性成分进行研究。方法将泽漆用95%乙醇渗漉提取后再用石油醚萃取得到脂溶性成分,用气相色谱-质谱联用仪(GC-MS)对其进行分析和鉴定。结果从泽漆中共分离鉴定出24种成分,占流出峰总面积的87.93%。主要成分依次为24-亚甲基环木菠萝烷醇(21.84%)、棕榈酸(15.79%)、羽扇豆醇(10.91%)、乙酸羽扇醇酯(10.51%)、棕榈酸乙酯(7.35%)、羽扇烯酮(4.20%)和β-谷甾醇(3.14%)。结论为进一步探讨泽漆药理作用及合理利用该植物资源提供了科学依据。Objective To analyze the chemical constituents of the liposoluble contents from Euphorbia helioscopia L. Methods The liposoluble contents from Euphorbia helioscopia L. were extracted by petroleum ether and then analyzed by GC - MS. Results 24 compounds were separated, identified and accounted for 87.93% of the total compounds. The major chemical constituents were 24 - methylenecyeloartanol 21.84% , hexadeeanoie acid 15.79% , lupeol 10.91%, lupeol acetate 10.51% , hexadeeanoic acid, ethyl ester 7.35% , lupenone 4.20% and β - sitosterol 3.14%. Conclusion The results will provide founda- tion for further exploitation and use of Euphorbia helioscopia L.

关 键 词：泽漆 脂溶性成分 气相色谱-质谱联用 

分 类 号：R284.1[医药卫生—中药学]