FTO： linking m^6A demethylation to adipogenesis  

作　　者：Moshe Shay Ben-Haim Sharon Moshitch-Moshkovitz Gideon Rechavi 

机构地区：[1]Sheba Cancer Research Center, Chaim ShebaMedieal Center, Tel Hashomer, 52621 Israel [2]Sackler School of Medicine, Tel Aviv University,Tel Aviv, 69978 Israel

出　　处：《Cell Research》2015年第1期3-4,共2页细胞研究（英文版）

摘　　要：Polymorphism of the FTO gene encoding an N^6-methyladenosine （m^6A） RNA demethylase was robustly associated with human obesity; however, the mechanism by which FTO affects metabolism, considering its emerging role in RNA modification, is still poorly understood. A new study published in Cell Research reports novel functions implicating FTO in the regulation of mRNA alternative splicing in the control of adipogenesis.

关 键 词：脂肪形成 FTO 去甲基化 平方 连接 基因编码 甲基化酶 控制调节 

分 类 号：Q785[生物学—分子生物学] S823.92[农业科学—畜牧学]