Aquaporin-dependent excessive intrauterine fluid accumulation is a major contributor in hyper-estrogen induced aberrant embryo implantation  

作　　者：Ying Zhang Qi Chen He Zhang Qiang Wang Rong Li Yaping Jin Haibin Wang Tonghui Ma Jie Qiao Enkui Duan 

机构地区：[1]State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2]Center of Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beij ing 100191, China [3]College of Basic Medical Sciences, Dalian Medical University, Dalian, Liaoning 116044, China [4]College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100. China

出　　处：《Cell Research》2015年第1期139-142,共4页细胞研究（英文版）

基　　金：This work was supported by the National Basic Research Program of China （2011CB944400, 2011CB710905, 2012CB944702 and 2015CB943000）, the Strategic Priority Research Program of the Chinese Academy of Sciences （XDA04020202-20 and XDA04020419） and the National Natural Science Foundation of China （31200879 and 31300957）.

摘　　要：Dear Editor, In mammalian species, the window of implantation is defined as a limited period when implantation-competent blastocyst can interact with the receptive endometrium [1]. Besides the acquisition of blastocyst competency and uterine receptivity, initiation of embryo implantation also involves a timely reabsorption of intrauterine fluids, which facilitates the apposition of embryo with the uterine lining [2]. These processes are coordinated by

关 键 词：胚胎植入 水通道蛋白 雌激素 异常 诱导 积液 过度 子宫内膜 

分 类 号：Q954.46[生物学—动物学] Q51