阴虚胃痛颗粒联合三联疗法治疗阴虚型慢性胃炎疗效观察  

Observation of effect of Yin deficiency stomach granule and triple therapy on Yin-deficiency type of chronic gastritis

作　　者：钱胜[1] 

机构地区：[1]江苏省常熟市中医院,江苏常熟215500

出　　处：《现代中西医结合杂志》2015年第5期478-480,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的观察阴虚胃痛颗粒联合三联疗法治疗阴虚型慢性胃炎的临床效果。方法将阴虚型慢性胃炎患者93例随机分为对照组45例和治疗组48例。对照组给予西医克拉霉素片、阿莫西林胶囊及果胶铋胶囊三联疗法治疗,治疗组则在对照组治疗基础上给予中成药阴虚胃痛颗粒治疗,2组均以7d为1个疗程,治疗6个疗程。观察2组治疗前后临床症状评分情况,用数字疼痛强度评估标尺(NRS)评判患者治疗前后疼痛情况,比较2组幽门螺杆菌转阴率及临床治疗的有效率。结果 2组治疗后胃脘隐痛或灼痛、口干舌燥、大便干结等主要症状积分及疼痛NRS评分均显著下降(P均<0.05),且治疗组的改善程度均明显优于对照组(P均<0.05);治疗组幽门螺杆菌转阴率为92%,对照组为80%,2组比较差异无统计学意义(P>0.05);治疗组临床有效率为92%,对照组为71%,2组比较差异有统计学意义(P<0.05)。结论阴虚胃痛颗粒治疗慢性胃炎能有效改善患者临床症状,缓解患者的胃痛感,抑制幽门螺杆菌感染,效果显著,值得临床深入研究运用。Objective It is to investigate the clinical efficacy of Yin deficiency stomach granule and triple therapy on Yin-deficiency type of chronic gastritis.Methods 93 Yin-deficiency type patients with chronic gastritis were randomly divided into a control group of 45 cases and a treatment group of 48 cases.Patients in the control group were treated with conventional west-ern medicine triple therapy, such as clarithromycin tablets and amoxil capsule, colloidal bismuth pectin capsules; while pa-tients in the treatment group were treated with Yin deficiency stomach granule for oral treatment on the basis of foundation treatment, 7 days for a course, six courses for treatment.The improvement of clinical symptoms was observed, and the pain scored in pretherapy and post-treatment were evaluated by NRS, the negative conversion ratio and the effective rate of the two groups were compared.Results The main clinical symptoms of the patients in two groups, such as stomachache, thirsty and dry stool and NRS scores were improved clearly, and the symptom scores went down clearly（P〈0.05）, the degree of change in the treatment group was more pronounced, the difference is significant （ P〈0.05）; The negative conversion ratio for pa-tients in the treatment group is 92%, which was higher than that of the control group 80%, the difference was not significant （P〉0.05）;The efficiency for patients in the treatment group is 92%, while for patients in the control group is 71%.The clinical efficacy of the treatment group was higher than that of the control group, the difference was significant （P〈0.05）. Conclusion Yin deficiency stomach granule can nourish the stomach Yin and relieve stomachache pain, and inhibit Helico-bacter pylori infection in the treatment for chronic gastritis.It’ s the clinical common Chinese patent medicine for treating Yin deficiency type of chronic gastritis, the clinical effect is significant, and it is worthy of further research and development.

关 键 词：阴虚胃痛颗粒 三联疗法 阴虚型 慢性胃炎 

分 类 号：R573.3[医药卫生—消化系统]