前葡萄膜炎并发性白内障术中前房注射曲安耐德的临床观察  

Research of anterior chamber triamcinolone acetonide injection during surgery for complicated cata-ract due to anterior uveitis

作　　者：李月华[1] 张孝生[1] 卢弘[1] 

机构地区：[1]首都医科大学附属北京朝阳医院眼科,100020

出　　处：《中华眼外伤职业眼病杂志》2015年第1期10-14,共5页Chinese Journal of Ocular Trauma and Occupational Eye Disease

摘　　要：目的前葡萄膜炎并发性白内障术中前房注射曲安耐德的有效性及安全性。方法前葡萄膜炎并发白内障40例（40只眼）随机分为两组：试验组（20只眼）和对照组（20只眼），所有患眼均行透明角膜切口晶状体超声乳化吸出联合人工晶状体植入术，术毕试验组前房内注射曲安耐德2mg，对照组不行曲安耐德注入。比较两组术后视力、眼压、角膜及前房反应的情况。结果术后视力比较，两组差异无统计学意义；术后1、3、7d试验组前房炎症反应明显低于对照组，差异有统计学意义；术后两组眼压及角膜内皮计数均在正常范围，差异无统计学意义。结论术中前房注射曲安奈德可减轻前葡萄膜炎并发性白内障人工晶状体植入术后前房渗出，是一种安全有效的给药方法，无明显不良反应。Objective To investigate the effect and the safety of triamcinolone acetonide（TA） in- jected in anterior chamber for patients who underwent the surgery for complicated cataract due to uveitis. Methods Forty eyes of 40 cases were divided into two groups randomly：the clinical trial group and control group. All patients underwent a clear corneal incision phacoemulsification combined with IOL implantation. TA 2mg was injected into anterior chamber during surgery in clinical trial group. Visual acuity, intraocular pressure （IOP）, corneal endothelial density and anterior chamber exudation were examined and compared be- tween two groups after surgery. Results Fibrin formation in trial group was significantly reduced than in control group and the difference was statistically significant. The differences in visual acuity, IOP and corne- al endothelial density were not statistically significant between two groups. Conclusion Anterior chamber injection of TA is an effective and safe way to decrease anterior chamber exudation after the surgery for com- plicated cataract due to anterior uveitis. No adverse event was observed.

关 键 词：曲安奈德 前房注射 白内障 并发性 前葡萄膜炎 

分 类 号：R779.6[医药卫生—眼科]