老年精神分裂症患者回溯性记忆和前瞻性记忆与社会功能的联系  

Relationship of Prospective Memory, Retrospective Memory and Social Function in Old Schizophrenics

作　　者：张勇[1] 邹义壮[1] 陈楠[1] 谢孟杰[1] 

机构地区：[1]北京大学精神卫生研究所,北京市100191

出　　处：《中国康复理论与实践》2014年第12期1158-1161,共4页Chinese Journal of Rehabilitation Theory and Practice

基　　金：首都医学发展科研基金项目(No.2009-1056)

摘　　要：目的探讨老年精神分裂症患者回溯性记忆(RM)和前瞻性记忆(PM)与社会功能的关系。方法选取老年精神分裂症患者54例及年龄、性别、受教育年限相匹配的正常对照54名。采用韦氏记忆量表第四版中文版(WMS-Ⅳ-C)中的逻辑记忆(LM-即时、LM-延迟)和剑桥前瞻性记忆测试量表(C-CAMPROMPT)分别评估被试的RM和PM,采用加州大学圣地亚哥分校基于任务的生活能力测验简版(UPSA-B)评估社会功能,采用韦氏成人智力量表第四版中文版(WAIS-Ⅳ-C)评估智商。结果患者组在LM-即时、LM-延迟、基于事件PM(EBPM)、基于时间PM(TBPM)、UPSA-B评分及智商均显著低于对照组(均P<0.001);在控制智商后,仍有非常高度显著性差异(P<0.001)。患者组UPSA-B总分与LM-即时(r=0.524,P<0.001)、LM-延迟(r=0.427,P<0.001)、EBPM(r=0.437,P<0.001)、TBPM(r=0.479,P<0.001)、智商(r=0.709,P<0.001)正相关,与年龄、病程的无显著相关性。线性逐步回归分析显示,TBPM(β=0.811,P=0.007)、智商(β=0.610,P<0.001)是UPSA-B评分的独立相关因素。结论精神分裂症患者存在PM和RM损伤,PM比RM对患者社会功能损伤的预测性更强。Objective To explore the relationship between prospective memory（PM）, retrospective memory（RM） and social function in old patients with schizophrenia. Methods 54 old patients with schizophrenia and 54 healthy controls were evaluated with logical memory（LM）IQ, LMIIQ of Wechsler Memory Scale-Fourth Edition（WMS-IV）, Chinese Cambridge Prospective Memory Test（C-CAMPROMPT）,University of California at San Diego（UCSD） Performance- based Skills Assessment- brief（UPSA- B）, and Wechsler Adult Intelligence Scale-Fourth Edition（WAIS-IV）. Results The scores of LMIQ, LMIIQ, event-based prospective memory（EBPM）, time-based prospective memory（TBPM）, IQ, and UPSA-B were poorer in the patients than in the controls（P〈0.001）. The score of UPSA-B was positively correlated with LMIQ（r=0.524, P〈0.001）, LMIIQ（r=0.427, P〈0.001）, EBPM（r=0.437, P〈0.001）, TBPM（r=0.479, P〈0.001） and IQ（r=0.709, P〈0.001）. Linear regression analysis indicated that TBPM（β =0.811, P=0.007）, IQ（β =0.610, P〈0.001） were contributing factors for the score of UPSA- B. Conclusion Schizophrenics may complicate the impairment of PM and RM, and the former may be independent fluence to their social function.

关 键 词：精神分裂症 老年 前瞻性记忆 回溯性记忆 社会功能 

分 类 号：R749.3[医药卫生—神经病学与精神病学]